Results 61 to 70 of about 95,295 (264)

Sheath‐to‐Artery Diameter Ratio: A Robust Predictor of Early Access‐Site Adverse Events in Percutaneous Procedures

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Vascular access site complications (VASCs) remain an important source of morbidity following percutaneous interventions. Although the sheath‐to‐femoral artery ratio is a recognized risk factor in transcatheter aortic valve implantation (TAVI), its role across a broader range of femoral procedures is less well defined.
Eduardo Ismael Arteaga Chan, Claudia Lerma, Adriana Torres‐Machorro   +2 more
wiley   +1 more source

Experimental methods in chemical engineering: The scientific method versus engineering design methodology

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract Engineering graduate students confuse the scientific method and problem solving when presenting their pre‐doctoral exams and theses: Science discourse adopts question and hypotheses to assert and establish a study's rationale, while it is problem and objectives in engineering design.
Gregory S. Patience, Alexander R. P. Harrison, Nicolas A. Patience, Paul A. Patience, Robert S. Weber   +4 more
wiley   +1 more source

Spontaneous Suburothelial Hemorrhage: The Crucial Role of Radiology in Preventing Unnecessary Interventions

International Medical Case Reports Journal, 2023
Amanuel Yegnanew Adela,1,2 Nebiyu Endrias Beshada,3 Adriano Basso Dias,4 Satheesh Krishna,4 Tesfaye Kebede1 1Radiology Department, Tikur Anbessa Specialized Referral Hospital (TASH), Addis Ababa University, Addis Ababa, Ethiopia; 2Radiology Department ...
Yegnanew Adela A, Endrias Beshada N, Dias AB, Krishna S, Kebede T   +4 more
doaj  

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries, Alastair M. Kilpatrick, Kathleen M. Scullion, Rhona Aird, Lorraine Bruce, Maria Elena Candela, Tak Yung Man, Stuart J. Forbes, James W. Dear   +8 more
wiley   +1 more source

Genotype-phenotype correlations in patients treated with acenocoumarol / Corelaţii genotip-fenotip la pacienţii trataţi cu acenocumarol

Romanian Journal of Laboratory Medicine, 2014
Scop: Această cercetare are drept scop stabilirea unei corelaţii genotip-fenotip la pacienţii trataţi cu acenocumarol şi studierea factoriilor genetici (polimorfismele VKORC1 şi CYP2C9), care ar putea influenţa valorile INR în timpul iniţierii terapiei ...
Militaru Florentina Claudia, Vesa Ştefan Cristian, Crişan Sorin, Militaru Valentin, Trifa Adrian Pavel, Buzoianu Anca Dana   +5 more
doaj   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

Fine lines and thin margins: Nutritional and anticoagulation challenges in long-term mechanical circulatory support [PDF]

Hospital Pharmacology
Introduction: Patients receiving long-term mechanical circulatory support (MCS), including Left Ventricular Assist Device (LVAD) and total artificial heart (TAH), represent a high-risk population prone to thromboembolic and bleeding complications. Stable
Stefanović-Nešković Jelena R., Nešković Branimir D., Strugarević Evgenija D.   +2 more
doaj   +1 more source

Clinical Significance of Acute Kidney Injury in Idiosyncratic Drug‐Induced Liver Injury: A Multicentric Propensity Scores Matched Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical significance of acute kidney injury in idiosyncratic drug‐induced liver injury: a multicentric propensity scores matched study. Evidence about the role of acute kidney injury (AKI) in idiosyncratic drug‐induced liver injury (DILI) is still scarce.
José María Pinazo‐Bandera, Hao Niu, Juan Pedro Toro‐Ortiz, Inmaculada Medina‐Caliz, Judith Sanabria‐Cabrera, Aída Ortega‐Alonso, Mercedes Robles‐Díaz, Daniel Enrique Di Zeo‐Sanchez, Nelia Hernández, Fernando Bessone, Vinicius Nunes, Raymundo Paraná, M. Isabel Lucena, Raul J. Andrade, Ismael Alvarez‐Alvarez, Miren García‐Cortés   +15 more
wiley   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

ESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio, Cristiano Amarelli, Rosaria Chiappetti, Irene Mattucci, Veronica Flocco, Mahmoud Issa Rammal, Ciro Abete, Francesca Mazzella, Ciro Maiello, Pasquale Abete, Francesco Cacciatore   +10 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source