Results 31 to 40 of about 23,012 (258)
Advanced Science, EarlyView.A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung +15 more
wiley +1 more source
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Exposures to human pathogens and toxins in licensed facilities in Canada have been monitored by a federal surveillance system since 2015, yet the affected persons (APs) in these incidents remain uncharacterized. This study comprehensively describes APs, highlighting sector‐specific patterns and trends over time.
Emily F. Tran +4 more
wiley +1 more source
Three‐dimensional digital analysis of musteloid masticatory muscle architecture
The Anatomical Record, EarlyView.Musteloids span an enormous breadth of dietary modes within a single superfamily. In this study, we utilize digital dissection techniques to reconstruct the internal 3D anatomy of muscles within the musteloid feeding apparatus, and explore how dietary specializations might alter the size, orientation, and curvature of fascicles therein.
Cassidy E. Davis +6 more
wiley +1 more source
Protection against Mycobacterium ulcerans lesion development by exposure to aquatic insect saliva.
PLoS Medicine, 2007 BackgroundBuruli ulcer is a severe human skin disease caused by Mycobacterium ulcerans. This disease is primarily diagnosed in West Africa with increasing incidence. Antimycobacterial drug therapy is relatively effective during the preulcerative stage of
Laurent Marsollier +16 more
doaj +1 more source
Insect bites as a trigger factor of eosinophilic cellulitis
Annals of Agricultural and Environmental Medicine, 2019 Introduction The study presents the case report of a Wells Syndrome in a 18-year -ld female. Wells Syndrome is a rare inflammatory skin disorder which seems to present an abnormal eosinophilic response to a number of triggers.
Monika Kucharczyk +2 more
doaj +1 more source
Bite force estimates and morphological correlations of jaw muscles in parrots
The Anatomical Record, EarlyView.Abstract Parrots (Order: Psittaciformes) are renowned for their high bite force (BF) and morphological correlates thereof, including a highly mobile skull and two unique mandibular adductor muscles—m. pseudomasseter and m. ethmomandibularis, with the former being hypothesized to increase force output.
Ana Carolina L. Faillace +3 more
wiley +1 more source
Kissing Bug Intrusions into Homes in the Southwest United States
Insects, 2021 Kissing bugs readily enter homes in the Sonoran Desert and bite the residents. Their saliva is highly antigenic, causing local and systemic skin reactions and life-threatening anaphylaxis.
Stephen A. Klotz +2 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Amphisbaenians (Squamata: Amphisbaenidae) are fossorial reptiles with highly specialized cranial morphology, yet their fossil record is frequently limited by fragmentary preservation. This study provides a detailed osteological redescription of the skulls of Amphisbaena braestrupi and Amphisbaena laurenti from the Pleistocene of Lagoa Santa ...
Carolina L. Paiva +2 more
wiley +1 more source
REMEDY FOR THE PAIN OF INSECT BITES [PDF]
Journal of the American Medical Association, 1909 The bites of mosquitoes and various gnats, the stings of wasps, bees, etc., have often produced a considerable amount of pain and discomfort and even death has resulted as a consequence of such stings in human beings. No effective remedy, as far as I am aware, has been recommended for the alleviation of the suffering caused by these insects. The flesh
openaire +2 more sources
The Anatomical Record, EarlyView.Abstract The ‘Palaeogene strata’ of the Itaboraí Basin (upper Paleocene‐lower Eocene), Southeastern Brazil, has preserved 29 genera and almost 50 species of metatherians (about 65% of its mammalian diversity). Among them, Eobrasilia coutoi Simpson, 1947 is the most enigmatic due to its quite fragmentary nature.
Leonardo M. Carneiro +10 more
wiley +1 more source