Results 121 to 130 of about 56,149 (267)

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara   +4 more
wiley   +1 more source

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim   +4 more
wiley   +1 more source

Synergy between repellents and non-pyrethroid insecticides strongly extends the efficacy of treated nets against Anopheles gambiae. [PDF]

open access: yes, 2007
BACKGROUND: To manage the kdr pyrethroid-resistance in Anopheline malaria vectors, new compounds or new strategies are urgently needed. Recently, mixing repellents (DEET) and a non-pyrethroid insecticide (propoxur) was shown to be as effective as ...
Boko, Pélagie   +31 more
core   +1 more source

Bioelectrochemical single reactor for reductive and oxidative removal of trichloroethylene from contaminated groundwater

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Chlorinated aliphatic hydrocarbons such as trichloroethylene (TCE) are persistent groundwater contaminants due to improper disposal and low biodegradability. This work presents an innovative bioelectrochemical system for the integrated reductive/oxidative removal of TCE from contaminated water, implemented in a single tubular ...
Maria Presutti   +5 more
wiley   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt   +4 more
wiley   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Determinants of optimal insecticide resistance management strategies

open access: yes, 2020
The use of insecticides to control agricultural pests has resulted in resistance developing to most known insecticidal modes of action. Strategies by which resistance can be slowed are necessary to prolong the effectiveness of the remaining modes of ...
Helps, J. C.   +3 more
core   +1 more source

A genome‐integrated CRISPR/Cas12a system enables efficient genetic engineering in Xenorhabdus budapestensis XBD8

open access: yesNew Plant Protection, EarlyView.
We developed a genome‐integrated CRISPR/Cas12a system for Xenorhabdus budapestensis XBD8, which enables precise deletion or replacement of DNA fragments ranging from 379 to 45,168 bp, with a success rate exceeding 90%. Application of this tool for the dynamic regulation of fabclavine‐8 biosynthesis resulted in a 1.90‐fold increase in production ...
Wenfeng Gan   +4 more
wiley   +1 more source

A review of high nature value farming systems in Europe: Biodiversity, ecosystem services, drivers, innovations and future prospects

open access: yesPeople and Nature, EarlyView.
Abstract Farming systems of high natural and cultural value represent approximately 30% of farmlands in the European Union and are associated with a high species and habitat diversity and/or the presence of species of European conservation concern. This study aims to synthesize the existing knowledge on the assessment of biodiversity and ecosystem ...
Elsa Varela   +4 more
wiley   +1 more source

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