Results 131 to 140 of about 908,958 (293)

A Simple and Low-Cost CRISPR/Cas9 Knockout System Widely Applicable to Insects

Insects
The CRISPR/Cas9 gene-editing system is a standard technique in functional genomics, with widespread applications. However, the establishment of a CRISPR/Cas9 system is challenging. Previous studies have presented numerous methodologies for establishing a
Jun Cao, Keli Wu, Xin Wei, Jiaojiao Li, Chun Liu, Tingcai Cheng   +5 more
doaj   +1 more source

MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation

Advanced Science, EarlyView.
During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support
Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li   +10 more
wiley   +1 more source

Serine Hydroxymethyltransferase Modulates Midgut Physiology in Aedes aegypti Through miRNA Regulation: Insights from Small RNA Sequencing and Gene Expression Analysis

Biomolecules
Aedes aegypti mosquitoes are critical vectors of arboviruses, responsible for transmitting pathogens that pose significant public health challenges. Serine hydroxymethyltransferase (SHMT), a key enzyme in one-carbon metabolism, plays a vital role in ...
Qian Pu, Yujiao Han, Zhuanzhuan Su, Houming Ren, Qingshan Ou, Symphony Kashyap, Shiping Liu   +6 more
doaj   +1 more source

The Molecular Analysis of Hawaiian Bird Diets [PDF]

, 2018
The aim of this project is to utilize high-throughput molecular methods to investigate the diets of three non-native and one native Hawaiian bird species.
Scinto, Alissa C
core   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Unveiling the conserved mechanism of microsporidian vertical transmission: A comparative study of Nosema infection across host species

Virulence
Microsporidia, ubiquitous obligate intracellular parasites infecting a wide range of hosts from humans to economically vital animals, employ transovarial transmission (TOT) as their primary vertical transmission mode.
Chunxia Wang, Yongzhi Kong, Zishen Tang, Tongyu Luo, Xuanang Yang, Yongjun Zhang, Tian Li, Zeyang Zhou   +7 more
doaj   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source

The Bombyx mori singed Gene Is Involved in the High-Temperature Resistance of Silkworms

Insects
Temperature is an important factor in the growth, development, survival, and reproduction of organisms. The high-temperature resistance mechanism of insects may be significant for use in the prevention and control of insect pests.
Zhenye Liu, Cong Li, Wenyu Yang, Qiao Wu, Wenfu Xiao, Yan Zhu, Qiongqiong Wei, Zhanqi Dong, Guizheng Zhang, Cheng Lu, Minhui Pan, Peng Chen   +11 more
doaj   +1 more source

Insect Swarms [PDF]

Science, 1893
openaire   +3 more sources

Factors affecting the sticking of insects on modified aircraft wings [PDF]

Previous work showed that the total number of insects sticking to an aluminum surface was reduced by coating the aluminum surface with elastomers. Due to a large number of possible experimental errors, no correlation between the modulus of elasticity ...
Chitsaz-Z, M. R., Eiss, N. S., Wightman, J. P., Yi, O.   +3 more
core   +1 more source