Results 81 to 90 of about 10,885 (206)
History, EarlyView.Abstract In March 1976, around 2000 women from forty countries arrived at the Palais des Congrès in Brussels to participate in the first International Tribunal on Crimes Against Women. Explicitly positioning themselves against the United Nations‐led ‘International Year of the Woman’, the organizers and participants of the tribunal proclaimed a global ...
NIVEDITA JOON
wiley +1 more source
The British Journal of Sociology, EarlyView.ABSTRACT The article presents a sociological study of promise‐to‐marry ‘rape’ cases in India to illuminate the inner lives of intimacies. It argues that promise‐to‐marry cases cannot be understood merely as instances of deceptive sex, wherein the consent of the victim is vitiated by a false promise of marriage as a pretext for sexual intercourse ...
Monika
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ANZ Journal of Surgery, EarlyView.ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman +2 more
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BJU International, EarlyView.Objective To examine the role of health‐related quality of life (HRQoL) assessments and patient‐reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.
Mohammed El Bahnasawi +4 more
wiley +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Local Search and the Evolution of World Models
Topics in Cognitive Science, EarlyView., 2023 Abstract An open question regarding how people develop their models of the world is how new candidates are generated for consideration out of infinitely many possibilities. We discuss the role that evolutionary mechanisms play in this process. Specifically, we argue that when it comes to developing a global world model, innovation is necessarily ...
Neil R. Bramley +3 more
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Congenital Insensitivity to Pain and Anhidrosis
Archives of Plastic Surgery, 2016 Jin Yong Shin +4 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
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Targeting KRAS for cancer therapy
British Journal of Pharmacology, EarlyView.In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia +4 more
wiley +1 more source