Results 81 to 90 of about 721,748 (274)

Fast and Lean Immutable Multi-Maps on the JVM based on Heterogeneous Hash-Array Mapped Tries [PDF]

open access: yes, 2016
An immutable multi-map is a many-to-many thread-friendly map data structure with expected fast insert and lookup operations. This data structure is used for applications processing graphs or many-to-many relations as applied in static analysis of object ...
Steindorfer, Michael J.   +1 more
core   +1 more source

Interpreting the Object Constraint Language [PDF]

open access: yes, 1998
The Object Constraint Language (OCL), which forms part of the UML 1.1. set of modelling notations is a precise, textual language for expressing constraints that cannot be shown in the standard diagrammatic notation used in UML.
Hamie, Ali, Howse, John, Kent, Stuart
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Evaluation of contact stress distribution on the surface of tibial insert component: Finite element analysis [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST)
The purpose of this study was to evaluate and compare the contact stress distributions on the surface of the tibial insert between the posterior-stabilized (PS) and cruciate-retaining (CR) total knee arthroplasty (TKA).
Techin Seechaipat   +2 more
doaj  

Numerical and Experimental Studies of the ŁK Type Shaped Charge

open access: yesApplied Sciences, 2020
In this paper, the authors presented an analysis of the strengthening of the cumulative jet by the appropriate formation of the detonation wave front acting under the influence of high pressure on the liner.
Dariusz Pyka   +6 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Worldwide enucleation techniques and materials for treatment of retinoblastoma: an international survey.

open access: yesPLoS ONE, 2015
PurposeTo investigate the current practice of enucleation with or without orbital implant for retinoblastoma in countries across the world.MethodsA digital survey identifying operation techniques and material used for orbital implants after enucleation ...
Daphne L Mourits   +4 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Plasticity of the MFS1 Promoter Leads to Multidrug Resistance in the Wheat Pathogen Zymoseptoria tritici

open access: yesmSphere, 2017
The ascomycete Zymoseptoria tritici is the causal agent of Septoria leaf blotch on wheat. Disease control relies mainly on resistant wheat cultivars and on fungicide applications.
Selim Omrane   +7 more
doaj   +1 more source

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