Demonstration of silicon-on-insulator mid-infrared spectrometers operating at 3.8µm
, 2013 The design and characterization of silicon-on-insulator mid- infrared spectrometers operating at 3.8µm is reported. The devices are fabricated on 200mm SOI wafers in a CMOS pilot line.
Chen, Xia +8 more
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
High extinction ratio, low insertion loss, optical switch based on an electrowetting prism. [PDF]
Opt Express, 2020 Zohrabi M +3 more
europepmc +1 more source
Diffraction of sound by nearly rigid barriers [PDF]
The diffraction of sound by barriers with surfaces of large, but finite, acoustic impedance was analyzed. Idealized source-barrier-receiver configurations in which the barriers may be considered as semi-infinite wedges are discussed. Particular attention
Hadden, W. J., Jr., Pierce, A. D.
core +1 more source
Planar Large Core Polymer Optical 1x2 and 1x4 Splitters Connectable to Plastic Optical Fiber [PDF]
, 2013 We report about new approach to design and fabricate multimode 1 x 2 and 1 x 4 Y optical planar power splitter suitable for low-cost short distance optical network. The splitters were designed by beam propagation method using BeamPROP™ software.
Neruda, M., Prajzler, V., Spirkova, J.
core
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Design of optical fiber delay line with large delay range and low insertion loss
Frontiers in PhysicsFor the application of continuously adjustable optical fiber delay lines, a large delay range can increase the instrument’s measurement range. Increased insertion loss of components will reduce the signal-to-noise ratio of the collected signal ...
Kai Wang +6 more
doaj +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Micro-device for coupling, multiplexing and demultiplexing using elliptical-core two-mode fiber [PDF]
We propose and demonstrate experimentally a fiber optic micro-device that is capable of tunably splitting, multiplexing, and demultiplexing optical signals using elliptical-core two-mode optical fiber.
Claus, R. O. +4 more
core +1 more source