NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Public Involvement in the Evaluation of Local Government Public Health Interventions in the UK: Lessons From PHIRST Insight. [PDF]
Health ExpectWort GK +6 more
europepmc +1 more source
STEREO Spacecraft Provide Unprecedented Insight Into Solar Storms [PDF]
, 2009 Sims, David
core +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Pigeons, portals, and Pacman: Insightful problem solving and navigation using a touchscreen video game. [PDF]
J Exp Anal BehavRodrigues RS +3 more
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Cognitive Complaints in Schizophrenia: A Meta-Analysis of Studies Using the Subjective Scale to Investigate Cognition in Schizophrenia (SSTICS): Les plaintes cognitives dans la schizophrénie : Une méta-analyse des études utilisant la <i>Subjective Scale To Investigate Cognition in Schizophrenia</i> (SSTICS). [PDF]
Can J PsychiatryWhite N, Potvin S, Do A, Stip E.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Digital Assessment of Metacognition Across the Psychosis Continuum: Measures, Validity, and Clinical Integration-A Scoping Review. [PDF]
Medicina (Kaunas)Martiadis V +4 more
europepmc +1 more source