Results 91 to 100 of about 34,475 (222)

Discriminative Sleep Patterns of Alzheimer's Disease via Tensor Factorization [PDF]

open access: yesarXiv, 2019
Sleep change is commonly reported in Alzheimer's disease (AD) patients and their brain wave studies show decrease in dreaming and non-dreaming stages. Although sleep disturbance is generally considered as a consequence of AD, it might also be a risk factor of AD as new biological evidence shows.
arxiv  

Early warning signals for desynchronization in periodically forced systems [PDF]

open access: yesarXiv, 2020
Conditions such as insomnia, cardiac arrhythmia and jet-lag share a common feature: they are all related to the ability of biological systems to synchronize with the day-night cycle. When organisms lose resilience, this ability of synchronizing can become weaker till they eventually become desynchronized in a state of malfunctioning or sickness.
arxiv  

Deep Convolutional Neural Networks for Interpretable Analysis of EEG Sleep Stage Scoring [PDF]

open access: yesarXiv, 2017
Sleep studies are important for diagnosing sleep disorders such as insomnia, narcolepsy or sleep apnea. They rely on manual scoring of sleep stages from raw polisomnography signals, which is a tedious visual task requiring the workload of highly trained professionals.
arxiv  

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Associations between Japanese calligraphy practice and sleep quality in community-dwelling older adults: A cross-sectional Study

open access: yesSleep Medicine: X
Background: Sleep disturbances, such as insomnia, are common among the elderly population and have been associated with negative health outcomes. Japanese calligraphy is a traditional art practice previously associated with various health benefits, such ...
Georg von Fingerhut   +6 more
doaj  

Association of insomnia symptoms and trajectories with the risk of functional disability: a prospective cohort study

open access: yesBMC Geriatrics
Background There is limited understanding regarding prospective associations of insomnia symptoms and trajectories with functional disability. We aimed to investigate the associations of insomnia symptoms and trajectories with functional disability ...
Qing-Mei Huang   +8 more
doaj   +1 more source

Demographic Differences in Insomnia and Anxiety and the Association with Cardiovascular Risk Factors among Jordanian Healthy Adult

open access: yesIranian Journal of Nursing and Midwifery Research
Background: Prior studies showed that anxiety and insomnia are both associated with Cardiovascular Disease (CVD). There is a lack of literature related to the prevalence of insomnia and anxiety among healthy adult populations in developing countries as ...
Ahmed Mohammad Al-Smadi   +7 more
doaj   +1 more source

Insomnia and Mild Cognitive Impairment

open access: yesGerontology and Geriatric Medicine, 2018
Insomnia is a common problem in older people, especially in patients with mild cognitive impairment (MCI) whose circadian rhythm is often compromised.
R. C. Hamdy MD   +6 more
doaj   +1 more source

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr   +12 more
wiley   +1 more source

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