Results 161 to 170 of about 401,827 (385)

Kaempferol Alleviates Acrolein‐Induced Lung Injury In Vitro and In Vivo by Binding to Peli2 and Disrupting the Peli2‐NLRP3 Interaction

open access: yesFood Frontiers, EarlyView.
Abstract Acrolein (ACR) is a highly toxic agent that induces lung inflammation and causes acute lung injury (ALI). However, effective treatments for ACR‐induced ALI are currently lacking. We investigated the protective effects of kaempferol (Kae) against ACR‐induced ALI using in vitro (HBE and BEAS‐2B cells) and in vivo murine models (male C57BL/6 mice)
Juanjuan Ma   +6 more
wiley   +1 more source

Suicide attempts among incarcerated homicide offenders [PDF]

open access: yes, 2015
The aim was to investigate the role of age, drug abuse, period of confinement, loneliness, difficulty in controlling emotions, having no friends in prison, victimization in prison, guilt over crimes, insomnia, nightmares, anxiety, depression, and mood ...
Boduszek, Daniel   +3 more
core  

Tea and Blood–Brain Barrier Homeostasis: Potential Mechanisms and Improvement Strategies

open access: yesFood Frontiers, EarlyView.
Abstract The blood–brain barrier (BBB), a selective interface regulating cerebral substance exchange, plays a crucial role in maintaining cognitive function and metabolic balance. While tea consumption has been traditionally associated with health benefits, its specific effects on BBB integrity warrant systematic investigation. This review demonstrates
Rongbosen Yue   +5 more
wiley   +1 more source

Late Toxicity and Long‐Term Quality of Life in Survivors of Cancer of the Major Salivary Glands More Than 5 Years After Diagnosis: A Multi‐National Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Because salivary gland cancers (SGC) are rare and include different tumor subtypes, data on their long‐term quality of life and late toxicities are sparse. Methods Multi‐national study including SGC survivors more than 5 years after diagnosis.
Susanne Singer   +26 more
wiley   +1 more source

Safety and Efficacy Findings From a Phase Ib/II Study of ASP‐1929 Photoimmunotherapy With Pembrolizumab in Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background ASP‐1929 photoimmunotherapy—cetuximab conjugated to IRDye 700DX and red light (690 nm) for localized drug activation—results in rapid, selective cell killing. Methods This phase Ib/II open‐label study evaluated ASP‐1929 photoimmunotherapy plus pembrolizumab in patients with recurrent/metastatic HNSCC (≥ 1 accessible lesion, PD‐L1 ...
David M. Cognetti   +17 more
wiley   +1 more source

Analisis Insomnia pada Penderita Diabetes Melitus [PDF]

open access: yes, 2017
Rest of sleep regulates insulin and glucose tolerance during night-time. Patients with DM often suffer insomnia due to metabolic disorders such as osmotic diuresis and dehydration as manifested by nocturia, stress, anxiety, increased cortisol and ...
Wahyuningsih, A. S. (Atik)
core  

Executive Pay Cuts and Executive Turnover

open access: yesHuman Resource Management, EarlyView.
ABSTRACT This study examines the impact of executive pay cuts on executive turnover. While previous research has largely focused on the drivers of pay increases of top management team (TMT) members or the effects of their relative pay standing on executive behavior, the prevalence and consequences of pay cuts have received limited attention. Drawing on
Steffen Burkert
wiley   +1 more source

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