Results 31 to 40 of about 950,100 (309)
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Savaş Yıllarında Menteşe Livası'ndaki İbtidaî Mekteplerinin Genel Durumu 1916-1917
Tanzimat dönemi, Osmanlı Devleti için büyük değişimi ifade etmektedir ve bu değişimden etkilenen alanlardan birisi de eğitimdir. 1869 yılında yürülüğe giren Maârif-i Umûmiye Nizamnâmesi ile ilk defa bu alanda etraflı bir düzenleme yapılmış ve devlet ...
Muttalip Şimşek
doaj
Wide-Area Vehicle-Drone Cooperative Sensing: Opportunities and Approaches
The last decade has witnessed unmanned aerial vehicles (UAVs) emerging as a powerful platform for various industrial and civilian applications. However, refrained by limited battery capacities, the hovering time of UAVs is still limited, impeding them ...
Kai Peng +6 more
doaj +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Evaluation of testing procedures for real-scale sewage pipes
Tests to determine the tightness of wastewater pipes can in some cases produce results that are worthy of discussion. Therefore, testing procedures for real-scale sewage pipes used for house connections were evaluated and data were statistically analysed.
S. Ulutaş, M. Wichern, B. Bosseler
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
This article highlights the key aspects of the official control procedures concerning quality and in the fight against food fraud in the oil sector implemented in Catalonia by the Ministry for Agriculture, Livestock, Fisheries and Food of the Government ...
G. Cugat, M. R. Biel
doaj +1 more source
New trends in visual inspection of buildings and structures: Study for the use of drones
Visual inspection is a very simple, non-destructive technique and usual in diagnosing buildings and structures’ conditions. It also plays an important role in the rapid assessment of constructive problems as well as in the definition of an appropriate ...
Falorca Jorge Furtado +2 more
doaj +1 more source
This paper presents a method of optimizing the design of robotic manipulators using a novel kinematic model pruning technique. The optimization departs from an predefined candidate linkage consisting of a initial topology and geometry.
Hannes Gamper +4 more
doaj +1 more source

