Results 51 to 60 of about 812,863 (268)

Building Trust from Farm to Fork in Organic Agriculture: A Closer Look at Inspection and Certification Systems

open access: yesTurkish Journal of Agriculture: Food Science and Technology
As the organic agriculture sector grows, the need for standards, inspection, and certification systems to ensure trust in organic products increases.
Yener Ataseven   +2 more
doaj   +1 more source

Unmanned Aerial Drones for Inspection of Offshore Wind Turbines: A Mission-Critical Failure Analysis

open access: yesRobotics, 2021
With increasing global investment in offshore wind energy and rapid deployment of wind power technologies in deep water hazardous environments, the in-service inspection of wind turbines and their related infrastructure plays an important role in the ...
Mahmood Shafiee   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Research on Quality Monitoring System of Power Supply Service

open access: yesDianxin kexue, 2014
Based on all-round marketing management philosophy,quality monitoring system of power supply service was proposed,an index system of quality evaluation for power supply service was constructed and the processes of abnormal work orders were presented in ...
Xin Huang, Yong Mo
doaj  

Adaptive robotic system for the inspection of aerospace slat actuator mount

open access: yesFrontiers in Robotics and AI
Introduction: Robotics uptake in the aerospace industry is low, mainly due to the low-volume/high-accuracy production that aerospace manufacturers require.
Nour M. Morsi   +3 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Inspection of the Madison Correctional Institution

open access: yes, 2006
Title from p. [1] of PDF document (viewed July 26, 2006).; "July 7, 2006."; Inspection date (unannounced): April 24, 2006.; Harvested from the web on 7/26 ...
Ohio. Correctional Institution Inspection Committee.
core  

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