Results 61 to 70 of about 2,293,047 (306)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Benefit or Burden? How English Schools Responded to the Duty to Promote Community Cohesion [PDF]

open access: yesJournal of Social Science Education, 2012
This paper discusses results from a small scale qualitative study of howprimary and secondary schools in three English local authorities respondedto the introduction and subsequent inspection of a legal duty to promotecommunity cohesion, following a ...
Don Rowe   +3 more
doaj  

Fatigue Risks in the Connections of Sign Support Structures [PDF]

open access: yes, 2013
This research effort develops a reliability-based approach for prescribing inspection intervals for mast-arm sign support structures corresponding to user-specified levels of fatigue-induced fracture risk.
Diekfuss, Joseph A.   +2 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Proposal of inspection method for isolation and vibration control devices using deep learning (Anomaly detection based on force-displacement relationship images of normal data)

open access: yesNihon Kikai Gakkai ronbunshu
This paper proposes a novel inspection system for seismic isolation and vibration control devices using unsupervised deep learning to enhance evaluation reliability and objectivity.
Tsuyoshi FUKASAWA, Satoshi FUJITA
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Developing an Ontology for Concrete Surface Defects to Enhance Inspection, Diagnosis and Repair Information Modeling

open access: yesInfrastructures
Facility maintenance requires thorough inspections throughout a facility’s lifecycle to ensure structural integrity and longevity. A significant challenge lies in managing the semantic relationships between various inspection data across different ...
Fardin Bahreini, Amin Hammad
doaj   +1 more source

Determination of strength criteria on conditions of visual testability of impact damage in composite aircraft constructions

open access: yesНаучный вестник МГТУ ГА, 2019
One of the principal criteria of aircraft composite design strength on the conditions of damage tolerance is the minimum defect size of accidental impact damage that is sure to be located during regular maintenance checks.
S. V. Dubinskiy   +2 more
doaj   +1 more source

Inspection control in the field of environmental protection [PDF]

open access: yesZbornik Radova: Pravni Fakultet u Novom Sadu, 2012
The Republic of Serbia has built an extensive and comprehensive system of inspection control in the field of environmental protection. Through the specialization on various environmental issues in different areas of social life it is provided the ...
Lončar Zoran
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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