Results 41 to 50 of about 311,327 (362)
Forms, Methods and Tools for Conducting Tax Control
CECCAR Business ReviewAccounting professionals must know the characteristics of each form of tax control, so as to know how to respond to the requests made by tax inspectors. In this paper we highlighted the characteristics of each form of tax control, especially those of tax
Elena STĂNCIULESCU
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
PCAOB inspection reports and audit quality
Journal of Accounting and Public Policy, 2009 Abstract With the creation of the Public Company Accounting Oversight Board (PCAOB), audit firm oversight shifted away from self-regulation to independent regulation. The inspections program is the central feature of the PCAOB. We examine whether PCAOB inspections are able to distinguish actual audit quality (as opposed to perceived) during the ...
GUNNY, Katherine A. +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Journal on Interactive Systems, 2023 The Modeling Language for Interaction as Conversation (MoLIC) is an epistemic tool inspired by Semiotic Engineering to model (human-computer) interaction through diagrams.
Beatriz Brito do Rêgo +3 more
doaj +1 more source
Report of the Section of Apiary Inspection [PDF]
Journal of Economic Entomology, 1915 n ...
openaire +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2018 Significant Properties (SPs) have been in the digital preservation literature for a decade or more. There has been widespread agreement on the important role they play, but no consensus on exactly *what* is significant.Investigating the Significant Properties of Electronic Content over Time (InSPECT) aimed to expand and articulate the concept of ...
Knight, Gareth +3 more
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source