Results 51 to 60 of about 277,776 (266)

Laser Damage Inspection Final Report [PDF]

open access: yes, 2001
Large, high-power laser systems are often designed as reimaging multipass cavities to maximize the extraction of energy from the amplifiers. These multipass cavities often have vacuum spatial filters that suppress the growth of beam instability via B-integral effects.
Salmon, J T   +7 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Structural pest management: Characteristics of decay and insect attack in California homes

open access: yesCalifornia Agriculture, 1988
California's structural pest control industry is one of the most tightly regulated in the United States. One requirement is that a copy of each standard inspection report be filed with the state.
A Brier, W Dost, W Wilcox
doaj  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Technical specifications on harmonised epidemiological indicators for biological hazards to be covered by meat inspection of farmed game [PDF]

open access: yesEFSA Journal, 2013
In this report, harmonised epidemiological indicators are proposed for foodborne biological hazards to public health that are related to farmed game and meat thereof and that can be addressed within meat inspection.
European Food Safety Authority
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

A failed review of CCE site inspection standards and processes

open access: yesChiropractic & Manual Therapies, 2019
Background Accreditation of educational programs involves an independent agency assessing quality against a set of defined standards. Site inspection teams are appointed by an accrediting agency and compile a report with the intention of identifying ...
Stanley I. Innes   +2 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Transfer learning on convolutional activation feature as applied to a building quality assessment robot

open access: yesInternational Journal of Advanced Robotic Systems, 2017
We propose an automated postconstruction quality assessment robot system for crack, hollowness, and finishing defects in light of a need to speed up the inspection work, a more reliable inspection report, as well as an objective through fully automated ...
Lili Liu   +5 more
doaj   +1 more source

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