Results 51 to 60 of about 20,083,524 (351)

The Real Effects of PCAOB Inspection Reports on the M&A Deals of Non-Big 4 Accounting Firms

Accounting Review
Mergers and acquisitions (M&As) are an important way for non-Big 4 accounting firms to grow their businesses. Non-Big 4 firms also account for the vast majority of PCAOB inspections.
Clive Lennox, Xi Wu
semanticscholar   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Inspection of the Lorain Correctional Institution [PDF]

, 2006
Title from p. [1] of PDF document (viewed July 3, 2006).; Date of inspection (unannounced): April 4, 2006.; "June 12, 2006."; Harvested from the web on 7/3 ...
Ohio. Correctional Institution Inspection Committee.
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Inspection of the Northeast Pre-Release Center [PDF]

, 2006
Title from p. [1] of PDF document (viewed July 17, 2006).; "June 28, 2006."; Date of inspection (unannounced): March 31, 2006.; Harvested from the web on 7/17 ...
Ohio. Correctional Institution Inspection Committee.
core  

Feedback on use of inspection reports of industrial establishments as teaching aids for process safety in the French chemical engineering curriculum

, 2020
Numerous teaching aids are available for process safety education. In this article, the contents of the public and mandatory inspection reports of industrial installations classified for environmental protection are used as teaching aids.
L. Perrin, A. Laurent
semanticscholar   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Inspection and evaluation of the Marion Juvenile Correctional Facility [PDF]

, 2006
Title from p. [1] of PDF document (viewed May 19, 2006).; "April 14, 2006."; Date of inspection: Sept.
Ohio. Correctional Institution Inspection Committee.
core  

Exploration and Practice of Annual Safety Report Regulation for Long-Distance Water Diversion Projects

Renmin Zhujiang, 2022
Long-distance water diversion projects are important strategic infrastructure to optimize the patterns of water resource allocation,which are characterized by long distances,many hydraulic structures,complex geological and environmental conditions,and ...
HU Jiang, MA Fuheng, SHENG Jinbao, DAI Zhanqiang, LI Shuncai, FU Youqun   +5 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source