Inspiratory Effort and Lung Mechanics in Spontaneously Breathing Patients with Acute Respiratory Failure due to COVID-19: A Matched Control Study. [PDF]
A great debate has started as to whether acute respiratory failure (ARF) induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease [COVID-19]) should be classified as a classic form of acute respiratory ...
Tonelli R +9 more
europepmc +2 more sources
Effects of non-invasive respiratory supports on inspiratory effort in moderate-severe COVID-19 patients. A randomized physiological study. [PDF]
Rationale and objective Various forms of Non-invasive respiratory support (NRS) have been used during COVID-19, to treat Hypoxemic Acute Respiratory Failure (HARF), but it has been suggested that the occurrence of strenuous inspiratory efforts may cause ...
Schifino G +9 more
europepmc +2 more sources
Inspiratory threshold loading negatively impacts attentional performance
RationaleThere are growing concerns over the occurrence of adverse physiologic events (PEs) occurring in pilots during operation of United States Air Force and Navy high-performance aircraft. We hypothesize that a heightened inspiratory work of breathing
Eli F. Kelley +2 more
doaj +2 more sources
Positive end-expiratory pressure limits inspiratory effort through modulation of the effort-to-drive ratio: an experimental crossover study. [PDF]
How assisted spontaneous breathing should be used during acute respiratory distress syndrome is questioned. Recent evidence suggests that high positive end-expiratory pressure (PEEP) may limit the risk of patient self-inflicted lung injury (P-SILI).
Widing H +5 more
europepmc +2 more sources
Central venous pressure swing outperforms diaphragm ultrasound as a measure of inspiratory effort during pressure support ventilation in COVID-19 patients. [PDF]
Purpose The COVID-19-related shortage of ICU beds magnified the need of tools to properly titrate the ventilator assistance. We investigated whether bedside-available indices such as the ultrasonographic changes in diaphragm thickening ratio (TR) and the
Lassola S +5 more
europepmc +2 more sources
Early Inspiratory Effort Assessment by Esophageal Manometry Predicts Noninvasive Ventilation Outcome in De Novo Respiratory Failure. A Pilot Study. [PDF]
Rationale: The role of inspiratory effort still has to be determined as a potential predictor of noninvasive mechanical ventilation (NIV) failure in acute hypoxic de novo respiratory failure.
Tonelli R +11 more
europepmc +2 more sources
Comparison of inspiratory effort with three variable-flow nasal continuous positive airway pressure devices in preterm infants: a cross-over study. [PDF]
Objective Patient’s work of breathing may vary between different neonatal nasal continuous positive airway pressure (NCPAP) devices. Therefore, we aimed to compare the inspiratory effort of three variable-flow NCPAP delivery systems used in preterm ...
Bordessoule A +5 more
europepmc +2 more sources
Obstructive sleep apnea (OSA) is characterized by collapse of the upper airways during sleep. The contribution of alterations in effort perception is not understood. This study investigated the response of inspiratory and quadriceps muscles to repetitive
Claire Griffith‐Mcgeever +4 more
doaj +2 more sources
Outcomes of ventilatory asynchrony in patients with inspiratory effort. [PDF]
Objective To identify the relationship of patient-ventilator asynchrony with the level of sedation and hemogasometric and clinical results. Methods This was a prospective study of 122 patients admitted to the intensive care unit who underwent > 24 hours ...
Martos-Benítez FD +6 more
europepmc +2 more sources
Background In pressure-controlled (PC) ventilation, tidal volume (V T) and transpulmonary pressure (P L ) result from the addition of ventilator pressure and the patient’s inspiratory effort.
Nuttapol Rittayamai +6 more
doaj +2 more sources

