Results 61 to 70 of about 2,791,109 (272)

Pendelluft in hypoxemic patients resuming spontaneous breathing: proportional modes versus pressure support ventilation

Annals of Intensive Care, 2023
Background Internal redistribution of gas, referred to as pendelluft, is a new potential mechanism of effort-dependent lung injury. Neurally-adjusted ventilatory assist (NAVA) and proportional assist ventilation (PAV +) follow the patient’s respiratory ...
Daniel H. Arellano, Roberto Brito, Caio C. A. Morais, Pablo Ruiz-Rudolph, Abraham I. J. Gajardo, Dannette V. Guiñez, Marioli T. Lazo, Ivan Ramirez, Verónica A. Rojas, María A. Cerda, Juan N. Medel, Victor Illanes, Nivia R. Estuardo, Alejandro R. Bruhn, Laurent J. Brochard, Marcelo B. P. Amato, Rodrigo A. Cornejo   +16 more
doaj   +1 more source

Diaphragm shear modulus reflects transdiaphragmatic pressure during isovolumetric inspiratory efforts and ventilation against inspiratory loading [PDF]

Journal of Applied Physiology, 2019
The reference method for the assessment of diaphragm function relies on the measurement of transdiaphragmatic pressure (Pdi). Local muscle stiffness measured using ultrafast shear wave elastography (SWE) provides reliable estimates of muscle force in locomotor muscles. This study aimed at investigating whether SWE could be used as a surrogate of Pdi to
Bachasson, Damien, Dres, Martin, Nierat, Marie-Cecile, Gennisson, Jean-Luc, Hogrel, J.Y., Doorduin, J., Similowski, T.   +6 more
openaire   +3 more sources

Guiding Inspiratory Flow: Development of the In-Check DIAL G16, a Tool for Improving Inhaler Technique

Pulmonary Medicine, 2017
Portable inhalers are divisible into those that deliver medication by patient triggering (pMDIs: a gentle slow inhalation) and those that use the patient’s inspiratory effort as the force for deaggregation and delivery (DPIs: a stronger deeper ...
Mark Jeremy Sanders
doaj   +1 more source

Identifying asynchronies: Reverse trigger

Journal of Mechanical Ventilation, 2022
A variety of asynchronies between the patient’s respiratory efforts and the programed ventilatory settings have been categorized. Reverse trigger is described as an inspiratory effort occurring after a ventilator-initiated breath and may represent a ...
Víctor Perez, Jamille Pasco
doaj   +1 more source

Helium-Oxygen in the Postextubation Period Decreases Inspiratory Effort

American Journal of Respiratory and Critical Care Medicine, 2001
After tracheal extubation, upper and total airway resistances may frequently be increased resulting in an increase in inspiratory effort to breathe. We tested whether breathing a helium-oxygen mixture (HeO(2)) would reduce inspiratory effort in the period after extubation.
Jaber, S, Carlucci, A, Boussarsar, M, Fodil, R, Pigeot, J, MAGGIORE, Salvatore Maurizio, Harf, A, Isabey, D, Brochard, L.   +8 more
openaire   +4 more sources

Orthopnea and inspiratory effort in chronic heart failure patients

Respiratory Medicine, 2003
Orthopnea is a typical feature of patients with chronic heart failure (CHF), the factors contributing to it are not completely understood. We investigated changes in dyspnea and other respiratory variables, induced by altering posture (from sitting to supine) in 11 CHF patients (NYHA classes II-IV) and 10 control subjects.We measured dyspnea (Borg ...
Nava S, Larovere MT, Fanfulla F, Navalesi P, Delmastro M, Mortara A   +5 more
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Automatic Adjustment of the Inspiratory Trigger and Cycling-Off Criteria Improved Patient-Ventilator Asynchrony During Pressure Support Ventilation

Frontiers in Medicine, 2021
Background: Patient-ventilator asynchrony is common during pressure support ventilation (PSV) because of the constant cycling-off criteria and variation of respiratory system mechanical properties in individual patients.
Ling Liu, Yue Yu, Xiaoting Xu, Qin Sun, Haibo Qiu, Davide Chiumello, Davide Chiumello, Davide Chiumello, Yi Yang   +8 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source