Results 61 to 70 of about 27,214 (278)

Loading of trained inspiratory muscles speeds lactate recovery kinetics [PDF]

, 2010
Purpose: To investigate the effects of inspiratory muscle loading (ITL) and inspiratory muscle training (IMT) upon blood lactate concentration ([lacj]B)and acid-base balance following maximal incremental cycling.
Brown, PI, Johnson, MA, Sharpe, GR
core   +2 more sources

Spontaneous Inspiratory Effort During Lung-Protective Ventilation [PDF]

Respiratory Care, 2019
The reduction of tidal volume during controlled mechanical ventilation of patients with ARDS has proven to be one of the few specific interventions in critical care that can save lives.[1][1] Indeed, there is some evidence that lung-protective ventilation strategies, including tidal volume ...
openaire   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Respiratory Variations of Central Venous Pressure as Indices of Pleural Pressure Swings: A Narrative Review

Diagnostics, 2023
The measurement of pleural (or intrathoracic) pressure is a key element for a proper setting of mechanical ventilator assistance as both under- and over-assistance may cause detrimental effects on both the lungs and the diaphragm.
Michele Umbrello, Sergio Cereghini, Stefano Muttini   +2 more
doaj   +1 more source

Acoustical properties in inhaling singing : a case-study [PDF]

, 2017
A highly experienced versatile female professional singer displaying no apparent vocal complaint, developed inhaling singing, an innovative approach to reverse phonation.
Daemers, Kristin, Desmet, Frank, Leman, Marc, Moerman, Mieke, Raes, Godfried-Willem, Six, Joren, Vanhecke, Françoise   +6 more
core   +2 more sources

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

Risk Factors for Pulmonary Air Leak and Clinical Prognosis in Patients With COVID-19 Related Acute Respiratory Failure: A Retrospective Matched Control Study

Frontiers in Medicine, 2022
BackgroundThe role of excessive inspiratory effort in promoting alveolar and pleural rupture resulting in air leak (AL) in patients with SARS-CoV-2 induced acute respiratory failure (ARF) while on spontaneous breathing is undetermined.MethodsAmong all ...
Roberto Tonelli, Roberto Tonelli, Giulia Bruzzi, Linda Manicardi, Luca Tabbì, Riccardo Fantini, Ivana Castaniere, Ivana Castaniere, Dario Andrisani, Dario Andrisani, Filippo Gozzi, Filippo Gozzi, Maria Rosaria Pellegrino, Fabiana Trentacosti, Lorenzo Dall’Ara, Stefano Busani, Erica Franceschini, Serena Baroncini, Gianrocco Manco, Marianna Meschiari, Cristina Mussini, Massimo Girardis, Bianca Beghè, Alessandro Marchioni, Enrico Clini   +24 more
doaj   +1 more source

Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study. [PDF]

, 2015
BACKGROUND: Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic ...
A Hardwell, AH Boer de, AR Clark, BL Laube, Dinesh Saralaya, EF Juniper, F Lavorini, GM Hawksworth, H Chrystyn, H Chrystyn, H Chrystyn, H Chrystyn, Harold Hosker, Henry Chrystyn, JL Rau, JP Koning de, KR Chapman, L Bentur, ME Broeders, ME Broeders, MH Dewar, ML Everard, PH Brown, Philip Chetcuti, RA Al-Showair, V Giraud, W Azouz, W Azouz, Wahida Azouz, WE Kamin, WM Nsour   +30 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

Contribution of the diaphragm and the other inspiratory muscles to different levels of tidal volume and static inspiratory effort in the rabbit [PDF]

The Journal of Physiology, 1969
1. The contribution of the diaphragm and that of the other inspiratory muscles at different levels of tidal volume and during static inspiratory efforts of various strength has been studied in supine rabbits by blocking phrenic conduction with an electrotonic current. The rabbits were lightly anaesthetized with urethane and pentobarbitone.2. The volume
P, Mognoni, F, Saibene, G, Sant'ambrogio
openaire   +2 more sources