Results 71 to 80 of about 2,791,109 (272)

Respiratory Variations of Central Venous Pressure as Indices of Pleural Pressure Swings: A Narrative Review

Diagnostics, 2023
The measurement of pleural (or intrathoracic) pressure is a key element for a proper setting of mechanical ventilator assistance as both under- and over-assistance may cause detrimental effects on both the lungs and the diaphragm.
Michele Umbrello, Sergio Cereghini, Stefano Muttini   +2 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Impact of human behavior on inspiratory flow profiles in patients with pulmonary arterial hypertension using AOS™ dry powder inhaler device

Pulmonary Circulation, 2021
Relative to healthy subjects, patients with pulmonary arterial hypertension often present with decreased respiratory muscle strength, resulting in decreased maximum inspiratory pressure.
Sandeep Sahay, Royanne Holy, Shirley Lyons, Edwin Parsley, Mari Maurer, Jeffry Weers   +5 more
doaj   +1 more source

Risk Factors for Pulmonary Air Leak and Clinical Prognosis in Patients With COVID-19 Related Acute Respiratory Failure: A Retrospective Matched Control Study

Frontiers in Medicine, 2022
BackgroundThe role of excessive inspiratory effort in promoting alveolar and pleural rupture resulting in air leak (AL) in patients with SARS-CoV-2 induced acute respiratory failure (ARF) while on spontaneous breathing is undetermined.MethodsAmong all ...
Roberto Tonelli, Roberto Tonelli, Giulia Bruzzi, Linda Manicardi, Luca Tabbì, Riccardo Fantini, Ivana Castaniere, Ivana Castaniere, Dario Andrisani, Dario Andrisani, Filippo Gozzi, Filippo Gozzi, Maria Rosaria Pellegrino, Fabiana Trentacosti, Lorenzo Dall’Ara, Stefano Busani, Erica Franceschini, Serena Baroncini, Gianrocco Manco, Marianna Meschiari, Cristina Mussini, Massimo Girardis, Bianca Beghè, Alessandro Marchioni, Enrico Clini   +24 more
doaj   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Comparison of peak inspiratory flow rate via the Breezhaler®, Ellipta® and HandiHaler® dry powder inhalers in patients with moderate to very severe COPD: a randomized cross-over trial

BMC Pulmonary Medicine, 2018
Background The chronic and progressive nature of chronic obstructive pulmonary disease (COPD) requires self-administration of inhaled medication. Dry powder inhalers (DPIs) are increasingly being used for inhalation therapy in COPD.
Pablo Altman, Luis Wehbe, Juergen Dederichs, Tadhg Guerin, Brian Ament, Miguel Cardenas Moronta, Andrea Valeria Pino, Pankaj Goyal   +7 more
doaj   +1 more source

Surface EMG-based Quantification of Inspiratory Effort: A Quantitative Comparison with Pes [PDF]

, 2021
Jan Graßhoff, Eike Petersen, Franziska Farquharson, Max Kustermann, Hans‐Joachim Kabitz, Philipp Rostalski, Stephan Walterspacher   +6 more
openalex   +1 more source

Direction and Magnitude of Change in Plateau From Peak Pressure During Inspiratory Holds Can Identify the Degree of Spontaneous Effort and Elastic Workload in Ventilated Patients.

Critical Care Medicine, 2020
OBJECTIVES Inspiratory holds with measures of airway pressure to estimate driving pressure (elastic work) are often limited to patients without respiratory effort.
M. Kyogoku, T. Shimatani, J. Hotz, C. Newth, G. Bellani, M. Takeuchi, R. Khemani   +6 more
semanticscholar   +1 more source

Supraspinal fatigue in human inspiratory muscles with repeated sustained maximal efforts

Journal of Applied Physiology, 2020
When the inspiratory muscles are fatigued with repeated sustained maximal efforts, supraspinal fatigue, a component of central fatigue, contributes to the loss in maximal inspiratory pressure. The presence of supraspinal fatigue was confirmed by the increase in amplitude of twitch-like increments in pressure evoked by motor cortical stimulation during ...
Luu, BL, Saboisky, JP, Taylor, JL, Gorman, RB, Gandevia, SC, Butler, JE   +5 more
openaire   +3 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source