Results 1 to 10 of about 3,048,905 (395)

Influence of dynamic disturbance on rock creep from time, space and energy aspects

Geomatics, Natural Hazards & Risk, 2022
In order to explore the influence of dynamic disturbance on creep behavior of rock, the creep damage evolution in rock under the dynamic disturbance are reproduced with creep damage model.
Zhen Yang, Wancheng Zhu, Kai Guan, Baoxu Yan, Hanwen Jia   +4 more
doaj   +1 more source

Activation of the integrated stress response is a vulnerability for multidrug‐resistant FBXW7‐deficient cells

EMBO Molecular Medicine, 2022
FBXW7 is one of the most frequently mutated tumor suppressors, deficiency of which has been associated with resistance to some anticancer therapies. Through bioinformatics and genome‐wide CRISPR screens, we here reveal that FBXW7 deficiency leads to ...
Laura Sanchez‐Burgos, Belén Navarro‐González, Santiago García‐Martín, Oleksandra Sirozh, Jorge Mota‐Pino, Elena Fueyo‐Marcos, Héctor Tejero, Marta Elena Antón, Matilde Murga, Fátima Al‐Shahrour, Oscar Fernandez‐Capetillo   +10 more
doaj   +1 more source

A Numerical Model for the Compressive Behavior of Granular Backfill Based on Experimental Data and Application in Surface Subsidence

Metals, 2022
Granular backfill is generally confined in stopes to bear underground pressure in metal mines. Its mechanical behavior under lateral confinement is vital for controlling stope wall behavior and estimating surface subsidence in backfill mining operations.
Zhi-Hua Le, Qing-Lei Yu, Jiang-Yong Pu, Yong-Sheng Cao, Kai Liu   +4 more
doaj   +1 more source

Experimental and Numerical Study on the Anchorage Effect of Bolted Jointed Rock Masses

Frontiers in Earth Science, 2022
Anchor technology has become an irreplaceable geotechnical engineering reinforcement measure. To clarify anchorage effects and investigate the three-dimensional (3D) crack propagation process of bolted jointed rock masses, a series of physical model ...
Zhen Yang, Wancheng Zhu, Kai Guan, Baoxu Yan, Baoxu Yan, Wenjun Luo, Peng Liang   +6 more
doaj   +1 more source

A model for rock dissipated energy estimation based on acoustic emission measurements

Frontiers in Earth Science, 2023
The temporal domain of dissipated energy during rock damage and failure is commonly quantified using loading and unloading tests or elastic mechanics-based theoretical calculation methods. However, these approaches cannot be applied to obtain the spatial
Penghai Zhang, Kai Guan, Wenxue Deng, Xige Liu, Tao Qin, Qingshan Ma   +5 more
doaj   +1 more source

Stope structure evaluation based on the damage model driven by microseismic data and Mathews stability diagram method in Xiadian Gold Mine

Geomatics, Natural Hazards & Risk, 2021
To obtain a better economic benefit, Xiadian Gold Mine intended to increase the stope structure parameter from 2.5 m (height) to 8 m. A test stope using the new structure parameter was mined to verify the surrounding rock’s stability.
Honglei Liu, Yong Zhao, Penghai Zhang, Feiyue Liu, Tianhong Yang   +4 more
doaj   +1 more source

Commensal Fungus Candida albicans Maintains a Long-Term Mutualistic Relationship with the Host To Modulate Gut Microbiota and Metabolism

Microbiology Spectrum, 2022
Candida albicans survives as a commensal fungus in the gastrointestinal tract, and that its excessive growth causes infections in immunosuppressed individuals is widely accepted. However, any mutualistic relationship that may exist between C.
Doureradjou Peroumal, Satya Ranjan Sahu, Premlata Kumari, Bhabasha Gyanadeep Utkalaja, Narottam Acharya   +4 more
doaj   +1 more source

Pol32, an accessory subunit of DNA polymerase delta, plays an essential role in genome stability and pathogenesis of Candida albicans

Gut Microbes, 2023
Candida albicans is a pathobiont that inflicts serious bloodstream fungal infections in individuals with compromised immunity and gut dysbiosis. Genomic diversity in the form of copy number alteration, ploidy variation, and loss of heterozygosity as an ...
Shraddheya Kumar Patel, Satya Ranjan Sahu, Bhabasha Gyanadeep Utkalaja, Swagata Bose, Narottam Acharya   +4 more
doaj   +1 more source

Taming of Modulation Instability by Spatio-Temporal Modulation of the Potential [PDF]

, 2015
Spontaneous pattern formation in a variety of spatially extended nonlinear system always occurs through a modulation instability: homogeneous state of the system becomes unstable with respect to growing modulation modes.
Botey, M., Herrero, R., Kumar, S., Staliunas, K.   +3 more
core   +3 more sources

4-nitroquinoline 1-oxide induces immune cells death to onset early immunosuppression during oral squamous cell carcinoma development

Frontiers in Immunology, 2023
4-Nitroquinoline N-oxide (4-NQO) and its derivatives react with genomic DNA to form stable quinolone monoadducts, which are highly mutagenic and genotoxic.
Satya Ranjan Sahu, Satya Ranjan Sahu, Shweta Thakur, Doureradjou Peroumal, Bhabasha Gyanadeep Utkalaja, Bhabasha Gyanadeep Utkalaja, Abinash Dutta, Premlata Kumari, Premlata Kumari, Ipsita Subhadarsini, Ipsita Subhadarsini, Narottam Acharya   +11 more
doaj   +1 more source