Results 21 to 30 of about 3,165,406 (373)

Microsatellite instability: a review of what the oncologist should know

Cancer Cell International, 2020
The patients with high microsatellite instability (MSI-H)/mismatch repair deficient (dMMR) tumors recently have been reported that can benefit from immunotherapy, and MSI can be used as a genetic instability of a tumor detection index.
Kai Li, Haiqing Luo, Lianfang Huang, Hui Luo, Xiao Zhu   +4 more
semanticscholar   +1 more source

4-nitroquinoline 1-oxide induces immune cells death to onset early immunosuppression during oral squamous cell carcinoma development

Frontiers in Immunology, 2023
4-Nitroquinoline N-oxide (4-NQO) and its derivatives react with genomic DNA to form stable quinolone monoadducts, which are highly mutagenic and genotoxic.
Satya Ranjan Sahu, Satya Ranjan Sahu, Shweta Thakur, Doureradjou Peroumal, Bhabasha Gyanadeep Utkalaja, Bhabasha Gyanadeep Utkalaja, Abinash Dutta, Premlata Kumari, Premlata Kumari, Ipsita Subhadarsini, Ipsita Subhadarsini, Narottam Acharya   +11 more
doaj   +1 more source

Modified Zakharov equations for plasmas with a quantum correction [PDF]

, 2004
Quantum Zakharov equations are obtained to describe the nonlinear interaction between quantum Langmuir waves and quantum ion-acoustic waves. These quantum Zakharov equations are applied to two model cases, namely the four-wave interaction and the decay ...
Drummond J. E., F. Haas, Gradshteyn I. S., J. Goedert, Klimontovich Yu. L., L. G. Garcia, L. P. L. de Oliveira, Maafa N., Nicholson D. R., Thyagaraja A., Thyagaraja A., Zakharov V. E., Zakharov V. E.   +12 more
core   +2 more sources

Displacement Back Analysis for a High Slope of the Dagangshan Hydroelectric Power Station Based on BP Neural Network and Particle Swarm Optimization

The Scientific World Journal, 2014
The right bank high slope of the Dagangshan Hydroelectric Power Station is located in complicated geological conditions with deep fractures and unloading cracks.
Zhengzhao Liang, Bin Gong, Chunan Tang, Yongbin Zhang, Tianhui Ma   +4 more
doaj   +1 more source

Quantum Ergoregion Instability [PDF]

, 1997
We have shown that, as in the case of black holes, an ergosphere itself with no event horizon inside can evaporate spontaneously, giving energy radiation to spatial infinity until the ergoregion disappears.
Carter B., Starobinskii A.A.
core   +2 more sources

Targeting ATR and Chk1 kinases for cancer treatment: A new model for new (and old) drugs

Molecular Oncology, 2011
Trying to kill cancer cells by generating DNA damage is by no means a new idea. Radiotherapy and genotoxic drugs are routinely used in cancer therapy.
Luis I. Toledo, Matilde Murga, Oscar Fernandez‐Capetillo   +2 more
doaj   +1 more source

Spot Assay and Colony Forming Unit (CFU) Analyses–based sensitivity test for Candida albicans and Saccharomyces cerevisiae

Bio-Protocol, 2023
Cellular sensitivity is an approach to inhibit the growth of certain cells in response to any non-permissible conditions, as the presence of a cytotoxic agent or due to changes in growth parameters such as temperature, salt, or media components ...
Satya Sahu, Bhabasha Utkalaja, Shraddheya Patel, Narottam Acahrya   +3 more
doaj   +1 more source

cGAS surveillance of micronuclei links genome instability to innate immunity

Nature, 2017
DNA is strictly compartmentalized within the nucleus to prevent autoimmunity; despite this, cyclic GMP–AMP synthase (cGAS), a cytosolic sensor of double-stranded DNA, is activated in autoinflammatory disorders and by DNA damage.
K. Mackenzie, P. Carroll, Carol-Anne Martin, O. Murina, Adeline Fluteau, Daniel P. Simpson, Nelly N Olova, H. Sutcliffe, J. Rainger, Andrea K Robertson, R. Osborn, Ann Wheeler, M. Nowotny, N. Gilbert, Tamir Chandra, Martin A. M. Reijns, A. Jackson   +16 more
semanticscholar   +1 more source

Transition from Spin Dewetting to continuous film in spin coating of Liquid Crystal 5CB

Scientific Reports, 2018
Spin dewetting refers to spontaneous rupture of the dispensed solution layer during spin coating, resulting in isolated but periodic, regular sized domains of the solute and is pre-dominant when the solute concentration (C n ) is very low.
Palash Dhara, Nandini Bhandaru, Anuja Das, Rabibrata Mukherjee   +3 more
doaj   +1 more source

Thermodynamic and classical instability of AdS black holes in fourth-order gravity [PDF]

, 2014
We study thermodynamic and classical instability of AdS black holes in fourth-order gravity. These include the BTZ black hole in new massive gravity, Schwarzschild-AdS black hole, and higher-dimensional AdS black holes in fourth-order gravity.
Moon, Taeyoon, Myung, Yun Soo
core   +2 more sources