Results 41 to 50 of about 341,388 (268)

Transient Instability Mechanism and Control Method of PLL-Based Grid-Connected VSC

Zhongguo dianli, 2022
The transient instability mechanism and control method of grid-following control voltage source converter (VSC) are comprehensively studied to solve the transient instability of PLL (phase locked loop)-based VSC with consideration of the influence of ...
Zheng CHEN, Pengfei HU, Liyu DAI, Chaohui ZHOU, Yanxue YU, Xiaoqing XIU   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The influence of disturbance location and intensity on the deformation and failure of deep roadway surrounding rocks

Frontiers in Materials
The surrounding rocks in deep roadways frequently undergo dynamic disturbances caused by adjacent blasting or mining activities. These dynamic disturbances lead to the propagation and coalescence of cracks in the surrounding rock, inducing dynamic ...
Tao Zhang, Yunyun Xu, Chao Wei, Haijian Su, Yujie Feng, Liyuan Yu   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Mechanism and prevention of rockburst in deep asymmetric goaf areas coal seam main roadway

Meitian dizhi yu kantan
ObjectiveWith an increase in the utilization of main roadways in coal seams, rockburst have occurred increasingly more frequently in these main roadways.
Xihui LU, Weiwei ZHAO, Yinghao HAO, Anye CAO, Shijie SU, Guowei LYU, Gang BAI   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Characteristics of landslide movement and dynamic processes in Hongyacun landslide cluster, Qinghai Province, China

Frontiers in Earth Science
Landslide clusters pose significant threats to mountainous regions worldwide, with their complex failure mechanisms and dynamic behaviors requiring comprehensive investigation.
Gang Wei, Gang Wei, Zejun Xia, Zejun Xia, Jinkai Yan, Bin Li, Bin Li, Bin Li, Xinning Wu, Xinning Wu   +9 more
doaj   +1 more source