Results 121 to 130 of about 723,392 (313)

On using simulation to model the installation process logistics for an offshore wind farm [PDF]

open access: yes, 2017
The development of offshore wind farms (OWFs) in Europe is progressing to sites which are characteristically further from shore, in deeper waters, and of larger scale than previous sites.
Akartunali, Kerem   +5 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Calculation and Analysis of Meshing Stiffness of Helical Gear Considering Installation Error

open access: yesJixie chuandong, 2017
The analysis calculation of meshing stiffness of helical gear is the basis for the study of gear dynamics. According to the gear meshing principle and coordinate transformation theory the finite element model of helical gear meshing with the installation
Liu Baoshan, Du Qungui, Wen Qi
doaj  

Stress field evolution and crack extension law of coal breaking with flexible cutting tools

open access: yesMeitan xuebao
Flexible cutting tools reaming is a new method of coal seam unloading pressure and enhancing permeability, in order to resolve the problem of insufficient ability of flexible cutting tools breaking coal at the present period, improve the performance of ...
Jianping WEI   +7 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

The Influence of Work Shift System, Work Pressure and Work Environment on Employee Performance Central Surgical Organization of Bhayangkara Hospital Kediri

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to determine how the influence of the work shift system (X1), work pressure (X2), and work environment (X1) on employee performance (Y) Central Surgical Installation Bhayangkara Kediri Hospital.
Gian Alfreda Wirawan, Acep Samsudin
doaj  

Installation Effects in Supersonic Aircrafts

open access: yes, 2016
Validerat; 20160414 (global_studentproject_submitter)
openaire   +1 more source

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