Results 51 to 60 of about 723,392 (313)
During continuous slab casting, strand electromagnetic stirring (S-EMS) has a significant effect on improving the slab quality. In the current work, a numerical model based on the practical slab continuous casting machine and coupled electromagnetic ...
Daiwei Liu +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The Influence of Interest and Creativity on Learning Achievement Students of SMKN 1 Tongkuno
This study aims to: (1) determine the effect of interest in learning on student achievement in the electrical installation engineering expertise program 11th class SMK Negeri 1 Tongkuno, and (2)To determine the effect of learning creativity on student ...
Usman Usman, Badiun Badiun, Nontje Sangi
doaj +1 more source
Propeller installation effects on turboprop acoustics [PDF]
Propeller installation options for a twin-engined turboprop aircraft are evaluated at cruise conditions, aiming to identify the quieter configuration. Computational fluid dynamics is used to investigate the near-field acoustics and transfer functions are employed to estimate the interior cabin noise.
Chirico, Giulia +2 more
openaire +1 more source
Hand tool permits shrink sizing of assembled tubing [PDF]
Portable tool sizes tubing ends without disassembling the tubing installation. The shrink sizing tool is clamped to the tubing and operated by a ratchet wrench.
Millett, A., Odor, M.
core +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
An investigation of the possible extent of the re-spending rebound effect in the sphere of consumer products [PDF]
A key method used to reduce the environmental impact of a product is to make it more energy efficient. Previous studies have found that the potential benefits from improved efficiency are often at least partially negated by increased use of the product.
Billett, EH, Chalkey, A, Harrison, DJ
core
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source

