Results 71 to 80 of about 723,392 (313)

Flight investigation of installation effects on a wedge nozzle installed on an underwing nacelle [PDF]

A flight research program was conducted using a modified F-106B aircraft with an underwing-nacelle - engine installation to investigate installation effects on a wedge nozzle with retracted shrouds from Mach 0.70 to 1.10.
Johns, A. L.
core   +1 more source

Numerical evaluation of the soil behavior during impact driving of pipe-piles [PDF]

, 2019
During the impact driving of pipe-piles, the soil is influenced in different ways including the void ratio, stress distribution, and plugging formation.
Aubram, Daniel, Bakroon, Montaser, Daryaei, Reza, Rackwitz, Frank   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

MatDEM-based study of disc cutter force model in open TBM tunnels: Incorporating installation radius and synergistic effects

Underground Space
The prediction of rock cutting force is critical for tunnel boring machine performance and cutterhead design. This paper presents a novel model for rock cutting force prediction based on the Colorado School of Mines (CSM) model, which incorporates the ...
Yadong Xue, Lushan Shu, Lan Zhao, Wei Luo, Yongfa Guo   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Mock-up development of new warship protective armor structure and feasibility analysis of ship installation

Zhongguo Jianchuan Yanjiu, 2017
To ensure the installation of the new design of protective armor structure on larger warships,a study into the installation process of the structure of this armor is carried out to improve installation efficiency and ensure the protective effect.
ZHENG Pan, LI Yongqing, ZHU Xi, XIONG Hu
doaj   +1 more source

Effects of installation caused flow distortion on noise from a fan designed for turbofan engines [PDF]

Far-field noise measurements were taken for three different installations of essentially the same fan. The installation with the most uniform inlet flow resulted in fan-blade-passage tone sound pressure levels more than 10 dB lower than the installation ...
Dittmar, J. H., Povinelli, F. P., Woodward, R. P.   +2 more
core   +1 more source

Misalignment diagnosis of a planetary gearbox based on vibration analysis [PDF]

, 2014
As a critical power transmission system, planetary gearbox is widely used in many industrial important machines such as wind turbines, aircraft turbine engines, helicopters.
Abdalla, Gaballa M., Ball, Andrew, Chen, Zhi, Gu, Fengshou, Tian, Xiange, Zhen, Dong   +5 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Effect of Relative Position of Two Sets of Outdoor Units Installed in Groove on Surrounding Thermal Environment

Zhileng xuebao, 2017
The installation conditions of two outdoor units were examined experimentally in an enthalpy-potential laboratory platform in this study. The influence of three installation conditions of outdoor unit on the surrounding thermal environment, air ...
Jin Wufeng, Liu Shuo, Xu Lei, Ren Liyue
doaj