Results 91 to 100 of about 450,100 (292)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Disposal of Petroleum Installations - Major Policy Issues [PDF]

open access: yes
Following the Brent Spar controversy, the OSPAR countries reached a unanimous agreement in 1998 for the future rules for disposal of petroleum installations.
Petter Osmundsen, Ragnar Tveterås
core  

Amphibians and Reptiles of United States Department of Defense Installations [PDF]

open access: yes, 2018
The U.S. Department of Defense (DoD) occupies approximately 10.1 million ha of land within the U.S. spanning most ecosystems contained therein. To date, no comprehensive agency-wide inventory of amphibian and reptile species has been compiled.
Lovich, Robert E.   +2 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Application of Synthesized Hydrates in the National Economy

open access: yesEnvironmental and Climate Technologies
The article analyses the thermodynamic conditions for long-term storage of hydrates and proposes a methodology for calculating the main thermodynamic parameters that ensure long-term stability of the structure of gas hydrates.
Pavlenko Anatoliy
doaj   +1 more source

Dispersed storage and generation case studies [PDF]

open access: yes
Three installations utilizing separate dispersed storage and generation (DSG) technologies were investigated. Each of the systems is described in costs and control. Selected institutional and environmental issues are discussed, including life cycle costs.
Bahrami, K.   +2 more
core   +1 more source

Saturday Extra: Guerilla Civic Engagement on the Landscape [PDF]

open access: yes, 2011
Over at Civil War Memory, Kevin Levin brought the community\u27s attention to some installations placed on the fences surrounding a few of the statues along Monument Avenue in Richmond, Virginia.
Rudy, John M.
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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