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RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Chilean Connection</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>ARQ</i>, 2003 </span><br><span class="r_content">Durante la segunda mitad del siglo XX el grupo francés Oulipo hizo una de las más lúcidas defensas del oficio. Descartando el genio como motor de la creatividad, centró en la fábrica (o en el obrador) sus expectativas: todos podemos hacer arte.</span><br><span class="r_sub"><i>Guillermo Tejeda, Rodrigo Chauriye</i></span><br><small><a href="https://doaj.org/article/caad4df8740643a3acb57ad3ed9c9322" target="_blank" rel="nofollow" title="doaj.org/article/caad4df8740643a3acb57ad3ed9c9322">doaj</a> </small>   <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70223" target="_blank" rel="nofollow">EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated </span><br><span class="r_sub"><i>Donovan Pineau<span id="ma_3" style="display:none">, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_3')">+36 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70223?mi=2or9o2m&af=R&AllField=installations&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70223?mi=2or9o2m&af=R&AllField=installations&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_3" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70223" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70223'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70223)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_3')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="http://revtn.ro/index.php/revtn/article/view/349" target="_blank" rel="nofollow">SPECIFIC EQUIPMENT AND IMPROVED PARAMETERS IN ULTRASONICALLY HYBRID ASSISTED PROCESSES</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Nonconventional Technologies Review</i>, 2021 </span><br><span class="r_content"> The paper deals with the main types of installations, tools and equipment used in ultrasonically hybrid assisted processes. The study provides information about the specific components which form an ultrasonic chain such as transducer, reflecting and ...</span><br><span class="r_sub"><i>Cornel Cristian Enciu<span id="ma_4" style="display:none">, Gabriela Pirvu (Ene), Liviu Daniel Ghiculescu</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_4')">+2 more</a></small></i></span><br><small><a href="https://doaj.org/article/38f1d5798c894014a2066d17ea9f1c93" target="_blank" rel="nofollow" title="doaj.org/article/38f1d5798c894014a2066d17ea9f1c93">doaj</a> </small>   <br></div><div class="r"><p class="r_title"><a href="https://core.ac.uk/download/pdf/6239187.pdf" target="_blank" rel="nofollow">Optimal Coverage of Installations in a Carbon Emissions Trading Scheme (ETS)</a> <b><a href="https://core.ac.uk/download/pdf/6239187.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"></span><br><span class="r_content">Trading schemes for emission allowances have become a panacea for nations aspiring to reduce their aggregate emissions of greenhouse gases from industry in a cost-effective manner.</span><br><span class="r_sub"><i>Ancev, Tihomir<span id="ma_5" style="display:none">, Betz, Regina, Sanderson, Todd</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_5')">+2 more</a></small></i></span><br><small><a href="https://core.ac.uk/works/2462653" target="_blank" rel="nofollow" title="core.ac.uk/works/2462653">core</a> </small>   <div id="more_5" style="display:none"><a href="http://purl.umn.edu/6047" target="_blank" rel="nofollow" title="purl.umn.edu/6047">purl.umn.edu</a><br> </div><small><a href="#" onClick="return toggle_div(this, 'more_5')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70226" target="_blank" rel="nofollow">IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.</span><br><span class="r_sub"><i>Miriam Yagüe‐Capilla<span id="ma_6" style="display:none">, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_6')">+9 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70226?mi=2or9o2m&af=R&AllField=installations&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70226?mi=2or9o2m&af=R&AllField=installations&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small>   <div id="more_6" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70226" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70226'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70226)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_6')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1051/matecconf/202438900015" target="_blank" rel="nofollow">Aspects regarding the influence of internal explosions over the maximum surface temperature for equipment with type of protection flameproof enclosure</a> <b><a href="https://www.matec-conferences.org/articles/matecconf/pdf/2024/01/matecconf_sesam2023_00015.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>MATEC Web of Conferences</i></span><br><span class="r_content">The type of protection flameproof enclosure “d” consists in placing the parts that could ignite an explosive atmosphere inside of an enclosure that can withstand the pressure developed during an internal explosion of an explosive mixture and which ...</span><br><span class="r_sub"><i>Moldovan Lucian<span id="ma_7" style="display:none">, Magyari Mihai, Darie Marius, Moldovan Clementina Sabina</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+3 more</a></small></i></span><br><small><a href="https://doaj.org/article/8b11606283af4099871f3ea5034e9764" target="_blank" rel="nofollow" title="doaj.org/article/8b11606283af4099871f3ea5034e9764">doaj</a> </small>   <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.1051%2Fmatecconf%2F202438900015" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1051/matecconf/202438900015'); alert('Copied the doi');">copy doi</a> <small>(10.1051/matecconf/202438900015)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://cupola.gettysburg.edu/cgi/viewcontent.cgi?article=1001&context=artcatalogs" target="_blank" rel="nofollow">Maren Hassinger: Lives</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2010 </span><br><span class="r_content">Gettysburg College’s Schmucker Art Gallery is pleased to present Maren Hassinger: Lives, an exhibition of the artist’s films, sculptures, and installations held in conjunction with the Central Pennsylvania Consortium Africana Studies Conference, “Public ...</span><br><span class="r_sub"><i>Egan, Shannon</i></span><br><small><a href="https://core.ac.uk/works/48201213" target="_blank" rel="nofollow" title="core.ac.uk/works/48201213">core</a> </small>   <br></div><div class="r"><p class="r_title"><a href="https://core.ac.uk/download/30611714.pdf" target="_blank" rel="nofollow">EU Emission trading – better job second time around?</a> <b><a href="https://www.econstor.eu/dspace/bitstream/10419/28516/1/538778229.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2007 </span><br><span class="r_content">The EU Emission Trading Scheme (EU ETS) for CO2-emissions from energy and industry installations reflects a paradigm shift towards market-based instruments for environmental policy in the EU. The centerpieces of the EU ETS are National Allocation Plans (</span><br><span class="r_sub"><i>Betz, Regina<span id="ma_9" style="display:none">, Rogge, Karoline, Schleich, Joachim</span>   <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+2 more</a></small></i></span><br><small><a href="https://core.ac.uk/works/8034321" target="_blank" rel="nofollow" title="core.ac.uk/works/8034321">core</a> </small>   <div id="more_9" style="display:none"><a href="http://www.isi.fraunhofer.de/isi-wAssets/docs/e-x/de/working-papers-sustainability-and-innovation/working-paper_eu-emission-trading.pdf" target="_blank" rel="nofollow" title="isi.fraunhofer.de/isi-wAssets/docs/e-x/de/working-papers-sustainability-and-innovation/working-paper_eu-emission-trading.pdf">isi.fraunhofer.de (pdf)</a><br> </div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1386/tear.8.2.181_1" target="_blank" rel="nofollow">Embodied in a metaverse: "anatomia" and "body parts"</a> <b><a href="http://research.sabanciuniv.edu/16980/1/ayiter_embodied-metaverse.pdf" target="_blank" rel="nofollow">[PDF]</a></b> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2010 </span><br><span class="r_content">In this paper, the artist/author wishes to examine corporeality in the virtual realm, through the usage of the (non)-physical body of the avatar. Two sister art installations created in the virtual world of Second Life®, both of which are meant to be ...</span><br><span class="r_sub"><i>Ayiter, Elif</i></span><br><small><a href="https://core.ac.uk/works/5014456" target="_blank" rel="nofollow" title="core.ac.uk/works/5014456">core</a> </small>   <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1386%2Ftear.8.2.181_1" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1386/tear.8.2.181_1'); alert('Copied the doi');">copy doi</a> <small>(10.1386/tear.8.2.181_1)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-environmental_sciences/" class="suggestion"onclick="show_loader();"><b>environmental sciences</b></a><br/><a href="/q-instalaciones/" class="suggestion"onclick="show_loader();"><b>instalaciones</b></a><br/><a href="/q-public_space/" class="suggestion"onclick="show_loader();"><b>public space</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"></div></div></div><div class="pagenav"><a href="/q-installations/p-7/" rel="nofollow"><b>previous</b></a>   <a href="/q-installations/p-6/" rel="nofollow">6</a>  <a href="/q-installations/p-7/" rel="nofollow">7</a>  <b>8</b>  <a href="/q-installations/p-9/" rel="nofollow">9</a>  <a href="/q-installations/p-10/" rel="nofollow">10</a>   <a href="/q-installations/p-9/" id="next" rel="nofollow"><b>next</b></a> </div><br></div> </div> <script>document.getElementById('loadingGif').style.display='none';</script><div style="width: 100%; height: 40px; bottom: 0px; background-color: #f5f5f5;"><div style="padding-left: 15px; padding-top: 10px"> <a href="/" rel="nofollow">Home</a> - <a href="/page-about/" rel="nofollow">About</a> - <a href="/page-disclaimer/" rel="nofollow">Disclaimer</a> - <a href="/page-privacy/" rel="nofollow">Privacy</a> </div></div> <link rel="stylesheet" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.4/themes/smoothness/jquery-ui.min.css"/> </body> </html>