Results 71 to 80 of about 6,330,812 (290)

La « visibilité des circuits courts » comme ressource commune

open access: yesRevue de la Régulation, 2020
The regional council of Provence-Alpes-Côte d’Azur decided to create an observatory for short food chains in 2010 with the aim of supporting their development.
Noé Guiraud, Juliette Rouchier
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Chercher avec des enfants : la nécessité du désapprentissage

open access: yesSociétés et Jeunesses en Difficulté, 2017
The two researches characteristically involve “weak actors” (Payet, Giuliani, Laforgue, 2008), respectively: Brazilian children from a “favela” (shanty town) and French children with special needs, integrating representations of the socially produced ...
Claire de Saint Martin, Daisy Queiroz
doaj  

Sustainability in Open Source Software Commons: Lessons Learned from an Empirical Study of SourceForge Projects [PDF]

open access: yesTechnology Innovation Management Review, 2013
In this article, we summarize a five-year US National Science Foundation funded study designed to investigate the factors that lead some open source projects to ongoing collaborative success while many others become abandoned. Our primary interest was to
Charles M. Schweik
doaj  

Legal Analysis as Institutional Imagination* [PDF]

open access: yesThe Modern Law Review, 1996
Abstract Legal analysis can become a master tool of institutional imagination in a democratic society. To see why and how it can serve this purpose we must begin by understanding what is most distinctive about Jaw and legal thought in the contemporary industrial democracies.
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Mixing Public and Private Agri-Environment Schemes: Effects on Farmers Participation in Quebec, Canada

open access: yesInternational Journal of the Commons, 2020
Incentive-based mechanisms, such as payments for ecosystem services (PES) are increasingly being employed to encourage adoption of biodiversity conservation practices in agriculture.
Alejandra Zaga-Mendez   +3 more
doaj   +1 more source

Atlantic trade and regional specialisation in nothern Spain 1550-1650: an integrated trade theory-institutional organisation approach [PDF]

open access: yes, 2001
Based on an in-depth study of the northern Spanish economy in the sixteenth and seventeenth centuries, this paper argues that commercial expansion was a major source of the diverging performance of European regions.
Grafe, Regina
core   +2 more sources

The Future of Institutional Repositories at Small Academic Institutions: Analysis and Insights [PDF]

open access: yes, 2015
Institutional repositories (IRs) established at universities and academic libraries over a decade ago, large and small, have encountered challenges along the way in keeping faith with their original objective: to collect, preserve, and disseminate the ...
Wu, Mary J
core   +3 more sources

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