Results 121 to 130 of about 4,277,731 (289)
Caught On Tape: Institutional Order Flow and Stock Returns [PDF]
Many questions about institutional trading can only be answered if one can track high-frequency changes in institutional ownership. In the US, however, institutions are only required to report their ownership quarterly in 13-F filings.
John Y. Campbell +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
TRANSACTIONAL COSTS OF RATIONAL NUTRITION: COMPARING NEOCLASSICAL AND INSTITUTIONAL APPROACHES
Russian Journal of Economics and Law, 2013 The article attempts to economically interpret the new and poorly researched object – rational nutrition. Comparing various theoretical approaches to these issues revealed the excellence of institutional paradigm, according to which the inappropriate ...
Yu. V. Dubrovskaya, R. I. Chupin
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
ON THE ISSUE OF THE EXACT CONTENT OF THE CATEGORY NATURAL MONOPOLY
Russian Journal of Economics and Law, 2007 The article investigates the issues of economic content of the category natural monopoly, as well as the legislative interpretation of this category. The author gives reasons for the necessity to consider a wider range of economic phenomena to be natural
M. B. Dyomin
doaj
Why is economic geography not an evolutionary science? Towards an evolutionary economic geography [PDF]
The paper explains the commonalities and differences between neoclassical, institutional and evolutionary approaches that have been influential in economic geography during the last couple of decades.
Koen Frenken, Ron A. Boschma
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Atlantic trade and regional specialisation in nothern Spain 1550-1650: an integrated trade theory-institutional organisation approach [PDF]
, 2001 Based on an in-depth study of the northern Spanish economy in the sixteenth and seventeenth centuries, this paper argues that commercial expansion was a major source of the diverging performance of European regions.
Grafe, Regina
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
IMPACT OF INSTITUTIONAL QUALITY ON HUMAN RIGHTS ABUSES IN TRANSITION ECONOMIES [PDF]
This purpose of this paper is to examine the direct effects of institutional quality on human rights abuses in transition economies. We make use of an alternative empirical approach for evaluation of institutional system’s development in transition ...
Tamazian, Artur +1 more
core +4 more sources