Results 121 to 130 of about 702,656 (279)
Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation
Advanced Science, EarlyView.FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin +14 more
wiley +1 more source
Unlocking the potential of contract farming: lessons from Ghana [PDF]
This paper analyses sorghum contract farming in north-east Ghana in order to explore ways of making such arrangements viable for small farmers. The analysis draws on the convergence of sciences approach, which sees both science and social relations ...
Kudadjie-Freeman, C. +2 more
core +1 more source
Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Advanced Science, EarlyView.Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
Households’ Indebtedness and Financial Fragility [PDF]
The paper studies the determinants of international differences in household indebtedness, and inquires whether indebtedness is associated with increased “financial fragility”, as measured by the sensitivity of household arrears and insolvencies to ...
Marco di Maggio +2 more
core
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Advanced Science, EarlyView.Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
DO MISSING INSTITUTIONAL ARRANGEMENTS BLOCK ENLARGEMENT OF WATER MARKETS? [PDF]
As we consider the potential for expanding water markets as a means to help prevent water shortages, it is clear that there is resistance to such an expansion.
Easter, K. William, Smith, Rodney B.W.
core +1 more source
Advanced Science, EarlyView.Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You +12 more
wiley +1 more source
If services aren't delivered, people won't pay: the role of measurement problems and monitoring in Payments for Environmental Services [PDF]
The idea of Payments for environmental services (PES) has an appealing simplicity, which may explain the success of the concept. However, successful projects are far limited though and two constraints have been identified in literature.
Meijerink, Gerdien W.
core +1 more source
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity
Advanced Science, EarlyView.A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee +6 more
wiley +1 more source