Results 61 to 70 of about 2,076,228 (266)

Participation in Professional Centres from the Perspective of Children's/Adolescent's Personal and School/Vocational Life Histories

Revija za Elementarno Izobraževanje
The paper deals with the field of participatory action of individuals placed in professional centres, which represents a special conceptual challenge in both the theory and practice of such engagement.
Mateja Marovič, Ana Bogdan Zupančič
doaj   +1 more source

Improving care quality and preventing maltreatment in institutional care – a feasibility study with caregivers

Frontiers in Psychology, 2015
Institutionalized children in low-income countries often face maltreatment and inadequate caregiving. In addition to prior traumatization and other childhood adversities in the family of origin, abuse and neglect in institutional care are linked to ...
Katharin eHermenau, Katharin eHermenau, Elisa eKaltenbach, Getrude eMkinga, Tobias eHecker, Tobias eHecker, Tobias eHecker   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Experiences and Perspective of Caretakers Working in Childcare Institutes in Delhi: A Qualitative Inquiry

Indian Journal of Social Psychiatry
Context: Institutional care is a common alternative for children who have been displaced from their homes due to a variety of socioeconomic factors. The quality of care and well-being of children in such institutions has been under research due to its ...
Prerna Sharma, Yashika Sharma
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Beyond legitimacy. Background and Deficits for the Formation of Deviant Identity of Children from Social homes

Проблеми на постмодерността, 2011
Life in the institution is a measure of child protection and both a cause the "identity crisis" of child without parental care in Bulgaria. Research has demonstrated that institutional care has detrimental impact on all aspects of child development and ...
Dilyana Keranova
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

OUTDOOR ACTIVITIES AND EXPERIENTIAL LEARNING WITH CHILDREN AND YOUTH FROM INSTITUTIONAL CARE

Research in Education and Rehabilitation
Children and youth in institutional care settings face compounded developmental risks, including trauma histories, attachment disruptions, and limited access to protective factors supporting resilience.
Danijel Vasilj, Lejla Musić
doaj   +1 more source

INSTITUTION CARE FOR THE FEEBLE-MINDED [PDF]

The Journal of Nervous and Mental Disease, 1889
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openaire   +1 more source