Results 41 to 50 of about 1,904,166 (240)

Cambiamento e stabilità nelle federazioni dell'Asia meridionale: India, Pakistan e Malesia

open access: yesGlocalism: Journal of Culture, Politics and Innovation, 2018
Despite sharing the same colonial heritage, over the past few decades the federal systems of India, Pakistan and Malesia have been changing in very different ways.
Enrico Ciappi
doaj   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

A BRIEF OVERVIEW ON EU INSTITUTIONAL CHANGE FROM FOUNDATION TO LISBON

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2012
Bu makale, AB kurumsal değişimini dört ana politik kurum Avrupa Komisyonu, Avrupa Parlamentosu, AB Konseyi ve Avrupa Konseyi ve üç AB Antlaşması’na odaklanarak incelemeyi amaçlamaktadır. Bu bağlamda, ilk olarak, AB’nin kuruluşundan Amsterdam Antlaşması’
Zerrin Savaşan
doaj   +1 more source

Institutional Change in Japan [PDF]

open access: yes, 2006
This is a new analysis of recent changes in important Japanese institutions. It addresses the origin, development, and recent adaptation of core institutions, including financial institutions, corporate governance, lifetime employment, and the amakudari system.
Blomström, Magnus, La Croix, Sumner J.
openaire   +2 more sources

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi   +4 more
wiley   +1 more source

Façonner des outils d’analyse pour étudier le changement institutionnel

open access: yesRevue de la Régulation, 2014
Most powerful analytical tools used in the social sciences are well suited for studying static situations. Static and mechanistic analysis, however, is not adequate to understand the changing world in which we live.
Elinor Ostrom, Xavier Basurto
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

On inevitability of political clientelism in contemporary Serbia [PDF]

open access: yesSociologija, 2016
This paper deals with the problem of political clientelism in Serbia broadly defined as the selective distribution of benefits (money, jobs, information, a variety of privileges) to individuals or clearly defined groups in exchange for political
Cvejić Slobodan
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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