Results 61 to 70 of about 23,831,433 (300)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Pressões da globalização e a resposta criadora

open access: yesCadernos EBAPE.BR
Este artigo aborda a globalização como um complexo processo de institucionalização e examina o potencial da teoria institucional na elucidação das características do fenômeno, em especial, na forma específica como se manifesta nas regiões periféricas ...
Luiz Alberto da Costa Mariz
doaj   +1 more source

Crossing the Next Meridian: The Economics of Rural-Urban Interdependence, Institutions, and Income Distribution in the American West

open access: yesJournal of Agricultural and Resource Economics, 1998
This article explores and develops three ideas: (a) that the aridity of western North America and its attendant characteristics have fundamentally shaped the work of western agricultural economists and encouraged some distinctive western contributions to
Bruce A. Weber
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Changement institutionnel et paiements pour services environnementaux au Cambodge : l’intérêt de l’approche Commonsienne

open access: yesDéveloppement Durable et Territoires, 2016
This article analyzes the processes of emergence and dissemination of PES schemes in Cambodia. Our analytical framework is based on the theory of institutional change of John R. Commons.
Colas Chervier   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

THE ROLE OF PRACTICES IN INSTITUTIONAL CHANGE THE EVOLUTION OF DOCTORAL PROGRAMS IN FRANCE 1990 – 2008 [PDF]

open access: yes
Whether based on the figure of institutional entrepreneur or the dynamic of social movements, models of institutional change have yet to solve the paradox of embedded agency.
Charles Dhanaraj   +2 more
core  

The effect of political leaders on economic growth through institutional change

open access: yesRomanian Economic Journal, 2015
The article summarizes the influence of political leaders on institutions which, according to institutional economics, directly influences economic growth.
Dóra Zolcsák
doaj  

Farvel til normalarbeidsdagen? – En studie av endring i Irland, Norge og Sverige

open access: yesTidsskrift for Samfunnsforskning, 2012
I tiden etter 1980 har ideer om fleksibilitet og deregulering preget debatter om regulering av arbeidstid. I denne artikkelen undersøkes det hvordan den regulerte normalarbeidsdagen har utviklet seg i løpet av de siste 30 år.
Heidi Nicolaisen
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

open access: yesFEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual   +3 more
wiley   +1 more source

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