Results 81 to 90 of about 4,318,404 (306)

DROUGHT, STRIFE, AND INSTITUTIONAL CHANGE [PDF]

open access: yes
Institutional and Behavioral Economics, Risk and Uncertainty,
Howitt, Richard E.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Preference formation and institutional change

open access: yesBrazilian Political Science Review, 2009
This essay critically analyses how historical institutionalists and rational choice scholars study institutional stability and change. Special attention is paid to the thorny issued of how political actors’ preferences are formed, with historical ...
Sérgio Praça
doaj  

Rights in the Time of Populism: Land and Institutional Change Amid the Reemergence of Right-Wing Authoritarianism in Colombia

open access: yesLand, 2019
In Colombia, right-wing leadership returned to power after winning the presidential elections in 2018 in a campaign in which they opposed the previous government, primarily because of the negotiations and peacemaking with the FARC-EP (Fuerzas Armadas ...
Sergio Coronado
doaj   +1 more source

Institutions and Institutional Change in Zambia [PDF]

open access: yes
Research has shown a positive correlation between extractive colonisation and low post-colonial economic growth. This paper provides case study research to explore the possibility that post-colonial extractive institutions were already present in pre ...
Sophia du Plessis
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Community engagement and financial arrangements: Navigating institutional change. [PDF]

open access: yesJ Clin Transl Sci, 2023
Sprague Martinez L   +7 more
europepmc   +1 more source

Paradigm Change/ Institute Change

open access: yes, 2014
We are in the midst of paradigm change, brought on by initiatives like biological systems theory, post-structuralism, James Gibson’s theory of affordances,1 and neuroplasticity.Top-down or prime-mover models of change have given way to principles of creative interactivity and causal pari-ty, in which ...
L.O. Aranye Fradenburg, Eileen A. Joy
openaire   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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