Results 81 to 90 of about 2,324,008 (310)
Crafting analytical tools to study institutional change
Most powerful analytical tools used in the social sciences are well suited for studying static situations. Static and mechanistic analysis, however, is not adequate to understand the changing world in which we live.
ELINOR OSTROM +3 more
core +1 more source
Shocks, institutional change, and sustainability transitions. [PDF]
Johnstone P, Schot J.
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Preference formation and institutional change
This essay critically analyses how historical institutionalists and rational choice scholars study institutional stability and change. Special attention is paid to the thorny issued of how political actors’ preferences are formed, with historical ...
Sérgio Praça
doaj
In Colombia, right-wing leadership returned to power after winning the presidential elections in 2018 in a campaign in which they opposed the previous government, primarily because of the negotiations and peacemaking with the FARC-EP (Fuerzas Armadas ...
Sergio Coronado
doaj +1 more source
Institutional change refers to the processes through which formal and informal rules governing social interaction are created, transformed, and replaced over time. Within the perspective of analytical sociology, institutional change is explained by identifying the micro-level mechanisms linking individual beliefs, preferences, and actions to macro ...
Huang Shaoan, Sun Shengmin
+6 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Complementarity and institutional change: How useful a concept? [PDF]
The concept of institutional complementarity – i.e. the idea that the co-existence of two or more institutions enhances the functioning of each – is increasingly used to explain why institutions are resistant to change and why introducing new ...
Deeg, Richard
core
Community engagement and financial arrangements: Navigating institutional change. [PDF]
Sprague Martinez L +7 more
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

