Results 101 to 110 of about 23,831,433 (300)
Complementarity and institutional change: How useful a concept? [PDF]
The concept of institutional complementarity – i.e. the idea that the co-existence of two or more institutions enhances the functioning of each – is increasingly used to explain why institutions are resistant to change and why introducing new ...
Deeg, Richard
core
Power and resistance in schools: Implementing institutional change to promote health equity for sexual and gender minority youth. [PDF]
Front Health Serv, 2022 Shattuck D +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Section Editorial: Supporting institutional change
Journal of Learning Development in Higher Education, 2021 Cathy Malone
doaj +1 more source
The biomedical informatics short course at Woods Hole/Georgia: Training to support institutional change. [PDF]
Inf Serv Use, 2022 Cimino JJ.
europepmc +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Political Entrepreneurship and Institutional Change: an Evolutionary Approach [PDF]
The paper is a contribution to the theory of institutional change. Using a process-based, evolutionary framework, a comparative analysis of economic and political entrepreneurship is provided and implications are derived for the role of political ...
Hederer, Christian
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
The impact of socio-economic institutional change on agricultural carbon dioxide emission reduction in China. [PDF]
PLoS One, 2021 Long DJ, Tang L.
europepmc +1 more source