Results 111 to 120 of about 2,324,008 (310)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
The institutional change and it´s implications on economic development [PDF]
The guide in the elaboration of this article was the work of the famous attorney of the new institutionalism, D. North, named “Institutions, Institutional Change and Economic Performance”.
Ramona Frunza, Marian Stanciu
core
Digital Transformation of Face-To-Face Focus Group Methodology: Engaging a Globally Dispersed Audience to Manage Institutional Change at the World Health Organization. [PDF]
J Med Internet Res, 2022 Gamhewage G +6 more
europepmc +1 more source
Evolution of Institutions or Institutional Change?
Journal of Institutional StudiesThe purpose of the article is to analyze the practices of using the expression "evolution of institutions" in the study of institutions to denote the processes and mechanisms of their emergence and change. Very often this means that the authors consider these processes and their mechanisms to be similar to those that operate within the framework of ...
openaire +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Governing the Resource: Scarcity-Induced Institutional Change [PDF]
We provide a dynamic model of natural resource management where the optimal institutional structure that governs resource use changes with resource depletion.
Nori Tarui, James Roumasset
core
Wrenching the machine around: EastEnders, the BBC and institutional change
, 2004 EastEnders is one of the most successful BBC programmes of recent years. Previous studies have concentrated on the text, its reception and its audiences.
McNicholas, A.
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Towards a quasi-Lamarckian theory of institutional change. [PDF]
The paper emphasises two flaws in mainstream economics: the failure to understand human behaviour and the belittling of transaction costs. By stressing the role of knowledge, institutions and path dependence, new institutional economics has provided a ...
Enrico Colombatto
core
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source