Results 91 to 100 of about 2,677,609 (309)

The role of contextual factors: institutional changes in the university system and in the labor market

open access: yes, 2020
The research we present extends our previous work on the individual determinants of student academic careers, by focusing on the role of institutional changes and labour market factors.
Dalit Contini   +3 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Institutional Analysis of Sesaot Forest Area Management West Nusa Tenggara Province

open access: yes, 2013
Sesaot forest area has been inhabited space shared between the parties. There are institutional HKm, either already use or not licensed. In the same space, there is a forest botanical garden institutions (Taman hutan raya/Tahura) who also did most of the
Hardiyanto, Gladi
core  

SOCIAL POLICY AS FACTOR OF STATE INSTITUTIONAL STATUS

open access: yesBaltic Journal of Economic Studies, 2016
The purpose of the article is the research of theoretical and methodological aspects of social policy as the factor of institutional state statuses. Methodology. The researching in institutional providing of state social policy which may be considered as
Larysa Zhukova
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Literature Review of Enterprise Systems Research Using Institutional Theory: Towards a Conceptual Model [PDF]

open access: yes
This paper sets out to examine the use of institutional theory as a conceptually rich lens to study social issues of enterprise systems (ES) research. More precisely, the purpose is to categorize current ES research using institutional theory to develop ...
Svejvig, Per
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

FORMATION AND DEVELOPMENT OF ENTREPRENEURSHIP AND BUSINESS IN RUSSIA IN XVII-XXI CENTURES

open access: yesВестник университета, 2019
The author explores the Russian business in the XVII-XXI centuries. based institutional approach, institutional factors reveals the formation and development of entrepreneurial activity.
S. Sazanova
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

INSTITUTIONAL CHANGES IN EMERGING EUROPE

open access: yes, 2015
The recent global economic crisis has created new conditions and situations for the economic environment and therefore, in this context the rethinking of the institutional system is mandatory.
AMARANDEI, Oana Georgiana
core  

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