Results 101 to 110 of about 12,394,917 (338)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

INSTITUTIONAL ENVIRONMENT OF FEMALE ENTREPRENEURS IN KAZAKHSTAN

Хабаршысы. Экономика сериясы, 2018
Positive trend on the number of female entrepreneurs in Kazakhstan has been noticed in recent years. Female entrepreneurs are provided with enormous opportunities in countries with transitional economy including Kazakhstan.
Р. Аман
doaj  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Do Ideas Matter in Strategic Choices Made by Organizations? An Empirical Work on the Participation of Agricultural Organizations to the Political Making Process in Costa Rica [PDF]

The new institutional economics has recently developed the idea that the institutional environment can have an impact on economic actors' mental perceptions, and reciprocally, that these perceptions can impact on the institutional environment.
D'Hotel, Elodie Maitre, le Cotty, Tristan   +1 more
core   +1 more source

An Empirical Study on Green Innovation Efficiency in the Green Institutional Environment

, 2018
Previous studies have found that reverse technology spillover effects can promote industrial technology modernization in developing countries. However, it is still unknown whether reverse technology spillover effects can improve green innovation ...
Yang Gao, S. Tsai, Xingqun Xue, Tingzhen Ren, Xiaomin Du, Quan Chen, Jiangtao Wang   +6 more
semanticscholar   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Empowering Rural People for Their Own Development [PDF]

This Elmhirst lecture first discusses the features of the institutional environment which allow rural people in low income countries to design, plan and implement their own rural development.
Binswanger, Hans P.
core   +1 more source

Prerequisites for Forming the Institutional Concept of the National Economy Competitiveness under Conditions of Globalization

Problemi Ekonomiki, 2015
The article attempts to prove that under conditions of globalization there have developed objective and subjective prerequisites for forming the institutional concept of the national economy.
Yaremenko Oleh L., Nasyrov Karim Z.
doaj  

ПРОБЛЕМИ ФОРМУВАННЯ В УКРАЇНІ МІНІМАЛЬНИХ ЗАПАСІВ НАФТИ ТА НАФТОПРОДУКТІВ

International Journal of Innovative Technologies in Economy, 2018
The article analyzes the current state of the institutional environment for the creation of minimum oil and petroleum products reserves in accordance with the documents of the Association of Ukraine with the EU.
Чукаєва І. К.
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source