Results 91 to 100 of about 3,743,455 (314)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
The Determinants of Institutional Quality. More on the Debate [PDF]
This paper provides new evidences about the determinants of institutional quality. Given the shortcomings of governance indicators, we first discuss the criteria employed to judge institutional quality.
Carlos Garcimartín +1 more
core +3 more sources
Development Studies Research, 2020 The Environmental Kuznets Curve (EKC) having been used to explain the relationship between growth and environmental degradation has gained some attention in the finance literature in recent times.
Matthew Ntow-Gyamfi +3 more
doaj +1 more source
Do high and volatile levels of public investment suggest misconduct ? the role of institutional quality [PDF]
This paper investigates the impact of institutional quality on public investment levels over the period 1984-2008. Moreover, it studies how the volatility of public investment and the quality of infrastructure are affected by institutional quality, and ...
Grigoli, Francesco, Mills, Zachary
core
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
EconomiesThis study investigates the firms’ performance following cross-border mergers and acquisitions (M&As) from 2000 to 2022, employing the generalized method of moments (GMM) technique within the French context.
Aamir Khan, David Kalisz
doaj +1 more source
Trade, Trust and Institutions [PDF]
To investigate the relation between trust and formal institutions, we analyze bilateral trade patterns in a sample of 16 European countries between 1996-2009. Trust in trading partners has a significant positive effect on bilateral trade.
Jakob de Haan +2 more
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Hurricanes and Long-term GDP Growth: The Role of Institutional Quality [PDF]
, 2016 This paper compares the long-term effects on real per-capita GDP of two hurricanes in 1992, hurricane Andrew in Florida and hurricane Iniki in Hawaii. The literature suggests that the long-term effect on GDP of a natural disaster for a region with good ...
Sakai, Kyoko
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Contractual Versus Non-Contractual Trade: The Role of Institutions in China [PDF]
Recent research has demonstrated the importance of institutional quality at the country level for both the volume of trade and the ability to trade in differentiated goods that rely on contract enforcement.
Barbara J. Spencer +3 more
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