Results 91 to 100 of about 24,289,840 (307)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Institutional Quality, Regulatory Environment and Microeconomic Performance: Evidence from Transition and Non-transition Developing Countries

open access: yesEast Asian Economic Review, 2021
The development of regulatory systems varies between transition and non-transition economies. This suggests that they provide different incentives for entrepreneurial development and could have varied effects on the economy because they have different ...
Haggai Kennedy Ochieng, Bokyeong Park
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Growth Effects of Institutional Instability [PDF]

open access: yes
Both institutional quality and institutional stability have been argued to stimulate economic growth. But to improve institutional quality, a country must endure a period of institutional change, which implies at least a little and possibly a lot of ...
Berggren, Niclas   +2 more
core  

Effect of Drug Cost-Exemption Policy on Treatment Outcomes in Multidrug-Resistant Tuberculosis Patients in Guangxi Zhuang Autonomous Region, China: A Nested Case–Control Study

open access: yesClinicoEconomics and Outcomes Research
Aimei Liu,1,* Yan Liao,2,* Juexian Ye,3,* Qing Wang,4 Junli Huang,5 Yucheng Tang,5 Lizhen Feng4 1Department of Infectious Diseases, Guangxi Zhuang Autonomous Region Chest Hospital, Liuzhou, People’s Republic of China; 2Department ...
Liu A   +6 more
doaj  

On the Effectiveness of Foreign Aid in Institutional Quality [PDF]

open access: yesSSRN Electronic Journal, 2013
We extend the Okada & Samreth (2012, EL) and Asongu (2012, EB) debate on ‘the effect of foreign aid on corruption’ by: not partially negating the former’s methodological underpinning (as in the latter’s approach) with a unifying empirical framework and; broadening the horizon of inquiry from corruption to eight institutional quality dynamics (rule of ...
openaire   +6 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Green innovation and environmental quality in Regional Comprehensive Economic Partnership (RCEP) countries: moderating effect of institutional quality

open access: yes
This study examines the role of institutional quality in the relationship between green innovation and environmental quality in RCEP countries, using a panel dataset covering the period from 2000 to 2021.
Hamzah, Hanny Zurina   +2 more
core   +1 more source

Foreign Direct Investment in Latvia and Serbia: A Comparative Analysis

open access: yesComparative Economic Research
The main purpose of this study is to compare foreign direct investment (FDI) patterns in Latvia and Serbia, ex­amining underlying trends, institutional frameworks, and historical contexts that shape investment dynamics.
Radovan Kastratović, Anatolijs Krivins
doaj   +1 more source

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