Results 91 to 100 of about 2,218,583 (314)

Green innovation and environmental quality in Regional Comprehensive Economic Partnership (RCEP) countries: moderating effect of institutional quality

open access: yes
This study examines the role of institutional quality in the relationship between green innovation and environmental quality in RCEP countries, using a panel dataset covering the period from 2000 to 2021.
Hamzah, Hanny Zurina   +2 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

The Growth Effects of Institutional Instability [PDF]

open access: yes
Both institutional quality and institutional stability have been argued to stimulate economic growth. But to improve institutional quality, a country must endure a period of institutional change, which implies at least a little and possibly a lot of ...
Berggren, Niclas   +2 more
core  

2008-2009 Factbook

open access: yes, 2021
NOTICE TO DATA USERS: Broncho Analytics (https://bronchoanalytics.uco.edu) provides data users with the most current institutional data available from the Office of Institutional Research.
UCO Office of Institutional Research
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Effect of Drug Cost-Exemption Policy on Treatment Outcomes in Multidrug-Resistant Tuberculosis Patients in Guangxi Zhuang Autonomous Region, China: A Nested Case–Control Study

open access: yesClinicoEconomics and Outcomes Research
Aimei Liu,1,* Yan Liao,2,* Juexian Ye,3,* Qing Wang,4 Junli Huang,5 Yucheng Tang,5 Lizhen Feng4 1Department of Infectious Diseases, Guangxi Zhuang Autonomous Region Chest Hospital, Liuzhou, People’s Republic of China; 2Department ...
Liu A   +6 more
doaj  

Foreign Direct Investment in Latvia and Serbia: A Comparative Analysis

open access: yesComparative Economic Research
The main purpose of this study is to compare foreign direct investment (FDI) patterns in Latvia and Serbia, ex­amining underlying trends, institutional frameworks, and historical contexts that shape investment dynamics.
Radovan Kastratović, Anatolijs Krivins
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Trade, Productivity and Institutional Quality: Issues and Empirics [PDF]

open access: yes
We estimate the relationship between productivity and trade for a panel of countries over the period 1980 to 2000 using instrumental-variables estimation of a productivity equation.
Martínez-Zarzoso, Inmaculada   +1 more
core  

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