Results 101 to 110 of about 3,743,455 (314)
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Institution building and political accountability [PDF]
, 2013 The paper examines the role of policy intervention in engendering institutional change. We show that first order changes in the political structure (e.g. introduction of democracy) may be undermined by local political interests and result in persistence
Majumdar , Sumon, Mukand, Sharun W.
core
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Institutional Quality and Trade in Pacific Island Countries [PDF]
This research examines the impact of institutional quality on trade in selected Pacific Island Countries (PICs). Four indicators of institutional quality are chosen: government effectiveness, rule of law, regulatory quality and control of corruption; for
Azmat Gani, Biman Chand Prasad
core
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
An Econometric Analysis of the Determinants of Foreign Direct Investment in Africa [PDF]
Romanian Economic Journal, 2018 This paper provides an empirical analysis on the determinants of FDI inflows in Africa. The dataset used for this paper spans from 1996-2016 and involves 48 African countries. For inferential analysis the paper employs random (RE) effect model.
Manamba Epaphra
doaj
On the Impact of Financial Inclusion on Financial Stability and Inequality: The Role of Macroprudential Policies [PDF]
, 2019 Financial Inclusion - access to financial products by households and firms - is one of the main albeit challenging priorities, both for Advanced Economies (AEs) as well as Emerging Markets (EMs), even more so for the latter.
El Said, A., Emara, N., Pearlman, J.
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
European Union Membership as a Shield? Corruption and Foreign Investment in Romania [PDF]
Romanian Journal of European AffairsThis study examines the intricate relationship between corruption and Foreign Direct Investment (FDI) in Romania, an emerging market and a European Union Member State that is undergoing significant institutional transformation.
Alexandra Horobeț +4 more
doaj
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source