Results 31 to 40 of about 160,098 (328)

The Future of Institutional Repositories

open access: yesEducation in the Knowledge Society, 2017
The institutional repositories are a fundamental component in the Open Science technological ecosystem. The green route for Open Access falls on them and, therefore, they are key in the new research policies that are described in the laws of science of ...
Francisco José GARCÍA PEÑALVO
doaj   +1 more source

Institutional repository

open access: yes, 2018
This is a simple presentation for comparing data repositories feodra, ckan, and dspase.
Ibaida Taha   +2 more
openaire   +1 more source

Institutional Repositories, Open Access and Copyright: What Are the Practices and Implications? [PDF]

open access: yes, 2016
A number of factors are driving open access to full-text journals: constantly rising prices of journal and database subscriptions, granting agencies requirements for recipients to submit their research publications into open access repositories, and ...
Dawson, Patricia H., Yang, Sharon Q.
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Knowledge Infrastructures Are Growing Up: The Case for Institutional (Data) Repositories 10 Years After the Holdren Memo

open access: yesData Science Journal
Institutional data repositories are uniquely positioned to support researchers in sharing scholarly outputs. As funding agencies develop and institute policies for research data access and sharing, institutional data repositories have emerged as a ...
Mikala R. Narlock   +4 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Moving data into and out of an institutional repository: Off the map and into the territory [PDF]

open access: yes, 2007
Given the recent proliferation of institutional repositories, a key strategic question is how multiple institutions - repositories, archives, universities and others—can best work together to manage and preserve research data.
Bishop, Libby
core  

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