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Knowledge Infrastructures Are Growing Up: The Case for Institutional (Data) Repositories 10 Years After the Holdren Memo

open access: yesData Science Journal
Institutional data repositories are uniquely positioned to support researchers in sharing scholarly outputs. As funding agencies develop and institute policies for research data access and sharing, institutional data repositories have emerged as a ...
Mikala R. Narlock   +4 more
doaj   +1 more source

Transforming the Quality of Metadata in Institutional Repositories

open access: yesThe Serials librarian, 2019
Established in 2005, the University of Nebraska–Lincoln (UNL)’s Libraries’ institutional repository (IR) has approximately 99,500 unique items. It is one of the largest and most-used institutional repositories in the United States.
M. Mering
semanticscholar   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice

open access: yesAging and Cancer, EarlyView.
Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth   +7 more
wiley   +1 more source

Moving data into and out of an institutional repository: Off the map and into the territory [PDF]

open access: yes, 2007
Given the recent proliferation of institutional repositories, a key strategic question is how multiple institutions - repositories, archives, universities and others—can best work together to manage and preserve research data.
Bishop, Libby
core  

Institutional repository

open access: yes, 2018
This is a simple presentation for comparing data repositories feodra, ckan, and dspase.
Ibaida Taha   +2 more
openaire   +1 more source

Obstacles to the Utilization of Institutional Repositories by Academics in Higher Education in Nigeria

open access: yesWebology, 2019
The purpose of this study was to identify the major barriers to the use of institutional repositories by academics in universities of Nigeria with a view to recommending ways of enhancing the utilization of institutional repositories.
S. Ukwoma, P. Ngulube
semanticscholar   +1 more source

ICU‐EEG Pattern Detection by a Convolutional Neural Network

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients in the intensive care unit (ICU) often require continuous EEG (cEEG) monitoring due to the high risk of seizures and rhythmic and periodic patterns (RPPs). However, interpreting cEEG in real time is resource‐intensive and heavily relies on specialized expertise, which is not always available.
Giulio Degano   +5 more
wiley   +1 more source

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