Results 131 to 140 of about 772,148 (335)

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

open access: yesAdvanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li   +3 more
wiley   +1 more source

Perception and Information Behaviour of Institutional Repository End-Users Provides Valuable Insight for Future Development. A Review of: St. Jean, B., Rieh, S. Y., Yakel, E., & Markey, K. (2011). Unheard voices: Institutional repository end-users. College & Research Libraries, 72(1), 21-42.

open access: yesEvidence Based Library and Information Practice, 2012
Objective – To determine the perceptions andinformation behavior of institutionalrepository (IR) end-users.Design – Semi-structured interviews.Setting – The interviews were conducted overthe telephone.Subjects – Twenty end-users of five differentIRs were
Lisa Shen
doaj  

Preserving institutional repositories

open access: yes, 2004
The Digital Preservation Coalition has posted a report summarizing the recent conference, Digital Preservation in Institutional Repositories (London, October 19, 2004). The report includes links to the separate presentations. Excerpt: 'The 9th DPC Forum was a collaboration between CURL and the British Library.
openaire   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

open access: yesAdvanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi   +10 more
wiley   +1 more source

Creating an Institutional Repository: LEADIRS Workbook [PDF]

open access: yes, 2004
The Learning About Digital Institutional Repositories Seminars programme (LEADIRS) aims to describe and illustrate how to build an online institutional repository.
Barton, Mary R., Waters, Margaret M.
core  

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

open access: yesAdvanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang   +22 more
wiley   +1 more source

Adopting a Distributed Model for Data Services

open access: yesCode4Lib Journal, 2017
This article describes how the Saint Edward’s University Library implemented a distributed model for the Institutional Repository. Based on Cloud Based platforms and APIs, the Library has created an Institutional Repository that is scaleable and modular,
Casey Gibbs   +2 more
doaj  

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

open access: yesAdvanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao   +8 more
wiley   +1 more source

Institutional repositories

open access: yes, 2006
Part of the book "Aspects of the Digital Library" - http://hdl.handle.net/1956 ...
openaire   +1 more source

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