Results 91 to 100 of about 2,212,735 (347)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Explanation of Mediator Role of Dynamic Capabilities in Relational View of Competitive Advantage Strategy [PDF]

open access: yesمطالعات مدیریت راهبردی, 2017
Today, companies are seen as part of the network of relationships that they can gain competitive advantage from networks. This study has been done to analyze the role of dynamic capabilities in relation between external relations of the organization with
Esmaeil Shahtahmasbi   +2 more
doaj  

Site-level evidence-based practice accreditation: A qualitative exploration using institutional theory. [PDF]

open access: yesHum Serv Organ Manag Leadersh Gov, 2023
Hall RL   +3 more
europepmc   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Identifying Gaps in Institutional Theory [PDF]

open access: yes, 2014
Institutional theory has been applied to various dimensions of extant IS literature. The major part of this literature, however, is dedicated to studying the influence of institutional isomorphic mechanisms at macro level in bringing legitimacy to ...
Geursen, Gus   +3 more
core  

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