Results 71 to 80 of about 2,252,012 (301)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Communities of Scholars: A Conceptual Scheme of Knowledge Production
Societies, 2018 This conceptual paper provides a meta-theoretical synthesis describing knowledge production processes in the sociological discipline. The first part of this paper gives an overview of recent studies exploring the sociological knowledge space with an ...
Konstantinos Zougris
doaj +1 more source
Organizational Institutionalism and Sociology: A Reflection [PDF]
, 2008 [Excerpt] In 1991, DiMaggio and Powell observed: Institutional theory presents a paradox. Institutional analysis is as old as Emile Durkheim\u27s exhortation to study \u27social facts as things\u27, yet sufficiently novel to be preceded by new in much of
Tolbert, Pamela S
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Schools of Education, Theory Production, and Institutional Reform
, 2005 The purpose of this brief study is to examine the constraints on theory production in schools of education, especially relative to Christian schools of ...
Loomis, Steve +2 more
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Sustainable Economic Development: Theory of Institutional Constructivism
Экономика: стратегия и практикаThe paper is devoted to the formulation of the problem of sustainable development of the intellectual economy and the use of the theory of constructivism in relation to solving the problems of institutional design of socio-economic systems.
E. A. Naumov
doaj +1 more source
Institutions as Knowledge Capital: Ludwig M. Lachmann’s Interpretative Institutionalism [PDF]
The paper revisits the socioeconomic theory of the Austrian School economist Ludwig M. Lachmann. By showing that the common claim that Lachmann’s idiosyncratic (read: eclectic and multidisciplinary) approach to economics entails nihilism is unfounded, it
Foss, Nicolai, Garzarelli, Giampaolo
core +1 more source
Comparative social capital: Networks of entrepreneurs and investors in China and Russia [PDF]
, 2005 Most studies on entrepreneurs’ networks incorporate social capital and networks as independent variables that affect entrepreneurs’ actions and its outcomes.
Batjargal, Bat
core +1 more source