Results 51 to 60 of about 776,534 (298)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Entrepreneurial Business and Economics Review, 2019 Objective: The objective of this article is to investigate the use of internationalisation to “escape” the institutional voids present in conflict economic systems, through interviews with fifteen Afghan family business leaders who run ...
Muska Hanify +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Understanding Entrepreneurship Through the Enrichment of Institutional Theory by Ethics
, 2015 [EN] This work offers a deeper evaluation of entrepreneurship through institutional theory understanding, in which the technical-economic sphere is not only complemented by a social perspective, but also structured and governed in an ethical manner ...
Alexis J. Bañón-Gomis +1 more
core +1 more source
Institutional Theories and Public Institutions: New Agendas and Appropriateness
, 2012 This chapter covers the evolution of institutional theory and its application to public adminsitrations in the last 20 years. It discusses the various streams, their reseach agendas and their contributions, but also their limits to add value to knowledge.
openaire +2 more sources
Speaking for human being: institutional logics, dragons, and the supra-human
Revista Eletrônica de Ciência AdministrativaThis essay engages with the mounting published criticism of neo-institutionalism, particularly the institutional logical approach. By addressing each of the main critiques formulated by the opponents of the theory – (1) institutional logical theory is ...
Roger Friedland, Diane-Laure Arjaliès
doaj +1 more source
Institutional differences in CEO sustainability messages: Text mining of Korean and global firms’ reports [PDF]
Problems and Perspectives in ManagementType of the article: Research Article AbstractSustainable management and corporate sustainability communication (CSC) have become central themes in both research and practice.
Tae-Il Yoon
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source