Results 61 to 70 of about 2,252,012 (301)

Speaking for human being: institutional logics, dragons, and the supra-human

Revista Eletrônica de Ciência Administrativa
This essay engages with the mounting published criticism of neo-institutionalism, particularly the institutional logical approach. By addressing each of the main critiques formulated by the opponents of the theory – (1) institutional logical theory is ...
Roger Friedland, Diane-Laure Arjaliès
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

TOURISM EMPLOYMENT AND ENTREPRENEURSHIP DYNAMICS IN WILDLIFE DESTINATIONS IN SOUTHERN AFRICA [PDF]

Revista Română de Geografie Politică
This study takes on a micro-institutional perspective to examine tourism employment and entrepreneurship dynamics within a complex socio-political and environmental Transfrontier Conservation Area context, using three destinations across Botswana ...
Refiloe J. LEKGAU, Tembi M. TICHAAWA
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

vSEMERA: pilot project assessing health profession students’ experiences in an international virtual research program

BMC Medical Education
Background The “Virtual Semester for Medical Research Aachen” (vSEMERA) is an international, interdisciplinary, virtual education program developed for health profession students.
Laura Bell, Eliana Lemos, Jan Krimphove, Stephanie Kaiser, Cristina Guerra-Giraldez, Martin Lemos   +5 more
doaj   +1 more source

Challenge of inclusive growth : global capitalization : institutional cost transferring and the economic of being poor = 包容性增長的挑戰: 全球資本化: 制度成本轉嫁與貧困經濟學

, 2011
My empirical research started with China’s experiment of rural reform during the 1980s-90s. According to the principle of experiment, only through a process of incessant falsification can we approach the truth.
WEN, Tiejun
core  

University governance and academic research : case studies of research units in Dutch and English universities [PDF]

, 2007
The central research question of our study addresses the effects of governing models on the research practices of basic research units in public universities in the fields of medieval history and biotechnology.
Leisyte, Liudvika
core   +1 more source

Social and cultural origins of motivations to volunteer a comparison of university students in six countries [PDF]

, 2010
Although participation in volunteering and motivations to volunteer (MTV) have received substantial attention on the national level, particularly in the US, few studies have compared and explained these issues across cultural and political contexts. This
Anne Birgitta Pessi, Astin, A.W., Astin, A.W., Astin, A.W., Baum, F.C., Bozzo, S., Civicus, Crosby, O., Davis Smith, J., Devlin, R.A., Esping-Anderson, G., Femida Handy, Friedland, L., Gabard, D.L., Gillespie, D., Grönlund, H., Hall, M., Hall, M., Hall, M., Handy, F., Independent Sector, Jeffrey L. Brudney, Jones, F., Jones, F., Lesley Hustinx, Musick, M.A., Naoto Yamauchi, O’Brein, E.M., Ram A. Cnaan, Salamon, L.M., Salamon, L.M., Salamon, L.M., Salamon, L.M., Smith, E., Taniguchi, H., Tuan, Y., Volunteering in America, Wikipedia, Winniford, J.C., Wuthnow, R., Yamauchi, N., Yu-Ting C.M.   +41 more
core   +1 more source