Results 1 to 10 of about 5,881,292 (359)

Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors

open access: yesScientific Reports, 2021
Prostate cancer (PCa) is a heterogeneous group of tumors with variable clinical courses. In order to improve patient outcomes, it is critical to clinically separate aggressive PCa (AG) from non-aggressive PCa (NAG).
Qing Kay Li   +13 more
doaj   +1 more source

Endoscopic through-the-scope suturing

open access: yesVideoGIE, 2022
Background and Aims: There is growing interest in closure of larger mucosal defects, given the increasing use of endoscopic resection for early GI neoplasia and the advent of submucosal endoscopy, including peroral endoscopic myotomy.
Linda Y. Zhang, MBBS   +3 more
doaj   +1 more source

Influence of Mechanical Properties on Modal Analysis of Natural Fiber Reinforced Laminated Composite Trapezoidal Plates

open access: yesJournal of Natural Fibers, 2021
Present work concentrates on modal parameters of laminated composite plates composed of natural fibers reinforced with unsaturated polyester resin. The selected jute and ramie fibers underwent alkaline treatment to improve mechanical properties.
D.R. Rajkumar   +2 more
doaj   +1 more source

Does endoscopic mean safer? A comparison of the short-term safety of endoscopic versus laparoscopic bariatric therapies

open access: yesEndoscopy International Open, 2022
Background and study aims There is minimal research on real-world, large-volume data comparing endoscopic bariatric therapy (EBT) to laparoscopic bariatric therapy (LBT).
Lea Fayad   +6 more
doaj   +1 more source

In situ transduction of cells in human corneal limbus using adeno-associated viruses: an ex vivo study

open access: yesScientific Reports, 2022
This study aimed to evaluate the efficacy of in situ adeno-associated virus (AAV)-mediated gene delivery into the human corneal limbal region via targeted sub-limbal injection technique.
Hyeck-Soo Son   +6 more
doaj   +1 more source

Rethinking the need for overnight admission after peroral endoscopic myotomy (POEM): a pandemic-driven approach to the future

open access: yesEndoscopy International Open, 2021
Background and study aims COVID-19 has significantly impacted endoscopic assessment and management of multiple conditions. Our group recommenced treatment of highly symptomatic achalasia patients (Eckardt score ≥ 6) adopting a same-day discharge (SDD ...
Linda Y. Zhang   +3 more
doaj   +1 more source

Proteomic signatures of 16 major types of human cancer reveal universal and cancer-type-specific proteins for the identification of potential therapeutic targets

open access: yesJournal of Hematology & Oncology, 2020
Background Proteomic characterization of cancers is essential for a comprehensive understanding of key molecular aberrations. However, proteomic profiling of a large cohort of cancer tissues is often limited by the conventional approaches.
Yangying Zhou   +13 more
doaj   +1 more source

First-in-human use of 11C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor 1 receptor

open access: yesEJNMMI Research, 2022
Purpose Study of the contribution of microglia to onset and course of several neuropsychiatric conditions is challenged by the fact that these resident immune cells often take on different phenotypes and functions outside the living brain.
Jennifer M. Coughlin   +15 more
doaj   +1 more source

Radiometric studies of mycobacterium tuberculosis

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1987
An in vitro assay system that included automated radiometric quantification of 14CO2 released as a result of oxidation of 14C- substrates was applied for studying the metabolic activity of M. tuberculosis under various experimental conditions.
Edwaldo E. Camargo   +4 more
doaj   +1 more source

Radiometric studies on the oxidation of (1-14c) fatty acids by drug-susceptible and drug-resistant mycobacteria

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1987
A radiometric assay system has been used to study oxidation patterns of (1-14C) fatty acids by drug-susceptible and drug-resistant organisms of the genus Mycobacterium. Two strains of M. tuberculosis susceptible to all drugs, H37Rv and Erdman, were used.
Edwaldo E. Camargo, M.d.   +4 more
doaj   +1 more source

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