Results 111 to 120 of about 8,809,521 (354)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Entrepreneurial entry: which institutions matter? [PDF]

open access: yes, 2009
In this paper we explore the relationship between the individual decision to become an entrepreneur and the institutional context. We pinpoint the critical roles of property rights and the size of the state sector for entrepreneurial activity and test ...
Aidis, R., Estrin, S., Mickiewicz, T.
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

LightTassel-YOLO: A Real-Time Detection Method for Maize Tassels Based on UAV Remote Sensing

open access: yes智慧农业
[Objective]The accurate identification of maize tassels is critical for the production of hybrid seed. Existing object detection models in complex farmland scenarios face limitations such as restricted data diversity, insufficient feature extraction ...
CAO Yuying   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Fibrodysplasia ossificans progressiva: from clinical complexity to therapeutic opportunity

open access: yesJournal of Rare Diseases
Fibrodysplasia Ossificans Progressiva (FOP) is an ultra-rare and severely disabling genetic disorder affecting approximately one in two million individuals worldwide. It is characterised by progressive endochondral heterotopic ossification (HO), in which
Amrita Chakraborty   +6 more
doaj   +1 more source

Territorial Institutions [PDF]

open access: yes
Territorial politics as social and political constructs are major issues for governement and for policy-making. Studying its properties and its dynamics shapes a domain of its own in social sciences.
Jean-Claude Thoenig
core  

Institutional Change and Institutional Persistence [PDF]

open access: yesSSRN Electronic Journal, 2020
Daron Acemoglu   +2 more
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Dyslipidemia and peripheral arterial disease

open access: yesIndian Heart Journal
Peripheral arterial disease (PAD) affects 12 % of adult population and is increasing globally and in India. Peripheral arterial disease when associated with atherosclerosis in two or more other arterial beds such as coronary artery disease (CAD ...
Ajay Yadav   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy